ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAVEVVMPKL GMAMKEGIIT SWNIKAGDNV AKGELIASIN SEKIETEIEA PADGTILDIA 

        70         80         90        100        110        120 
VSEDEGVPPG TVICYIGKPN EKVEVHESTK VEEELTASEV PQNVQHPEPL GKEVTNKQRI 

       130        140        150        160        170        180 
KISPVAKKIA KTENLDIRAL LGTGPGGRIT KVDVLKALEE RVAIPEVLEE SKVLPVTGMR 

       190        200        210        220        230        240 
KAIANRMHAS LQNSAQLTLT MKVDVTDLVA LHKEIAEVVQ KRYDNKLTIT DFVSRAVVLA 

       250        260        270        280        290        300 
LGEHKEMNSA YIDDAIHQFE HVHLGMAVAL EKGLVVPAIR FANNLSLVEL SKEIKNAAQK 

       310        320        330        340        350        360 
ARAGNLNSDD MQGTTFTISN LGSFGIEYFT PVLNTPETGI LGVGAIEHVP VYKGKKLKKG 

       370        380        390 
SMLPLSLTFD HRVLDGAPAA AFLRTIKRYL EEPVTILL 

References and documentation are available.

Number of amino acids: 398

Molecular weight: 43236.10

Theoretical pI: 5.89

Amino acid composition: 
Ala (A)  37	  9.3%
Arg (R)  13	  3.3%
Asn (N)  18	  4.5%
Asp (D)  16	  4.0%
Cys (C)   1	  0.3%
Gln (Q)   9	  2.3%
Glu (E)  37	  9.3%
Gly (G)  27	  6.8%
His (H)  10	  2.5%
Ile (I)  30	  7.5%
Leu (L)  39	  9.8%
Lys (K)  33	  8.3%
Met (M)  11	  2.8%
Phe (F)   8	  2.0%
Pro (P)  19	  4.8%
Ser (S)  19	  4.8%
Thr (T)  25	  6.3%
Trp (W)   1	  0.3%
Tyr (Y)   6	  1.5%
Val (V)  39	  9.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 53
Total number of positively charged residues (Arg + Lys): 46

Atomic composition:

Carbon      C	      1923
Hydrogen    H	      3162
Nitrogen    N	       518
Oxygen      O	       582
Sulfur      S	        12

Formula: C1923H3162N518O582S12
Total number of atoms: 6197

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    14440
Abs 0.1% (=1 g/l)   0.334, assuming all pairs of Cys residues form cystines


Ext. coefficient    14440
Abs 0.1% (=1 g/l)   0.334, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 37.66
This classifies the protein as stable.



Aliphatic index: 105.33

Grand average of hydropathicity (GRAVY): -0.056