ProtParam
User-provided sequence:
10 20 30 40 50 60
MAVFSKLQLL GQAIPPKQYA PGVVGMLAVF ALIKLYKQDI RGTKHLVAKT KKDGSKGQKA
70 80 90 100 110 120
HVDGVFLGKL ARILKILIPG FFSKESFYLI LIAVSLLCRT YADVYMIITS TKIEASIIDR
130 140 150 160 170 180
NPLLFALEAF KYVLNLPAIS VTNAILKFGI AELKLRFRER LSTHLYSQYL KGFTFYKMSN
190 200 210 220 230 240
LDTRIQNADQ LLTQDVDRFC DGIVELYSNL SKPILDVFLY LFRLGTSLGF SSPSILFSYL
250 260 270 280 290 300
LFTGVGLTYL RRPIGRLTVE EQALEGEYRY VNSRLIMNSE EIAFYQGNQS EKETIMSTFA
310 320 330 340 350 360
SLVQHLRKII LFRFSIGFVD NIVAKYLATV VGWYAVGSSF FDKQHKPFIG MSRNQLMQEY
370 380 390 400 410 420
YNSGRMMYKM AEALGRLALA GRDMTRLSGF TSRVDTLLNV LDDVNSGNYK RTMVGEKEES
430 440 450 460 470 480
SALIKSELVA GSGNLRVQDN VIRFDNVPLV TPNGDVLIER LNFEVPSGTN VLVCGPNGCG
490 500 510 520 530 540
KSSLFRVLGE LWPLFGGTLT KPAKGKLFYV PQRPYMTLGT LRDQIIYPDR PLDMIRKGVS
550 560 570 580 590 600
DSDLEQMLEN VQLTHILERE GGWSAVQDWM DVLSGGEKQR IAMARLFYHK PQFAILDECT
610 620 630 640 650 660
SAVSVDVEGA MYRLCREKNI TLFTVSHRKS LWKYHEYSLY MDGRGSYRFE QIDDQSDQFG
S
References and
documentation are available.
Number of amino acids: 661
Molecular weight: 74850.83
Theoretical pI: 9.14
Total number of negatively charged residues (Asp + Glu): 66
Total number of positively charged residues (Arg + Lys): 79
Atomic composition:
Carbon C 3396
Hydrogen H 5352
Nitrogen N 894
Oxygen O 957
Sulfur S 26
Formula: C
3396H
5352N
894O
957S
26
Total number of atoms: 10625
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 74065
Abs 0.1% (=1 g/l) 0.990, assuming all pairs of Cys residues form cystines
Ext. coefficient 73690
Abs 0.1% (=1 g/l) 0.984, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 38.68
This classifies the protein as stable.
Aliphatic index: 98.20
Grand average of hydropathicity (GRAVY): -0.031