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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAVKHKSESL KHEEGAAKKA KTGLLKLKKI MDIESNVVKY SICIPTTVID NCNNLEQVTF

70 80 90 100 110 120
TAYQIARTAV LFNVQEIIVL DQSKDKKHEK KSRSKETISD CLLLATLLQY FVTPPNLLDT

130 140 150 160 170 180
TFKKKNKLYL KCASTFPPLN QLPFMNASAE QHYKEGLSIA RDSSKGKSDD ALTNLVYIGK

190 200 210 220 230 240
NQIITLSNQN IPNTARVTVD TERKEVVSPI DAYKGKPLGY HVRMASTLNE VSEGYTKIVW

250 260 270 280 290 300
VNSGDFHYDE ELSKYHKVET KLPYIAKLKK SSTSEKPCNI LLIFGKWGHL KRCFRRSDLE

310 320 330 340
SSSLHHYFSG QLQFPASVPQ GNIPIQDSLP IALTMFQRWA S


References and documentation are available.

Number of amino acids: 341 Molecular weight: 38546.46 Theoretical pI: 9.33
Amino acid composition: 
Ala (A) 20 5.9% Arg (R) 10 2.9% Asn (N) 18 5.3% Asp (D) 15 4.4% Cys (C) 6 1.8% Gln (Q) 14 4.1% Glu (E) 19 5.6% Gly (G) 13 3.8% His (H) 10 2.9% Ile (I) 22 6.5% Leu (L) 35 10.3% Lys (K) 38 11.1% Met (M) 5 1.5% Phe (F) 12 3.5% Pro (P) 15 4.4% Ser (S) 31 9.1% Thr (T) 22 6.5% Trp (W) 3 0.9% Tyr (Y) 13 3.8% Val (V) 20 5.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 34 Total number of positively charged residues (Arg + Lys): 48 Atomic composition: Carbon C 1730 Hydrogen H 2766 Nitrogen N 464 Oxygen O 508 Sulfur S 11 Formula: C1730H2766N464O508S11 Total number of atoms: 5479 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 36245 Abs 0.1% (=1 g/l) 0.940, assuming all pairs of Cys residues form cystines Ext. coefficient 35870 Abs 0.1% (=1 g/l) 0.931, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 41.57 This classifies the protein as unstable. Aliphatic index: 88.06 Grand average of hydropathicity (GRAVY): -0.396