ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAVLSKLQLL NSTLTYKNWS PAFVGIFGCI TIAKIYSASF RNEGKGLSLS ETVGSGDVKK 

        70         80         90        100        110        120 
GKTKASLNAE FFAKLKKLLK ILIPGPFSSE VFYMIVIGFV LLARTIADVY MITNATSVEA 

       130        140        150        160        170        180 
SIVDRSPIMF AMSVFKYFLN LPAISLINAL LKFSLSELKL RFRENLTKYL YGKYLGGFTY 

       190        200        210        220        230        240 
YQISNLDSRI QNPDQLLTQD VEKFCDGIVE LYSNMTKPIL DVFLYVFKLG RALGWEGPGL 

       250        260        270        280        290        300 
LFGYLMASMV VLTKLRRPIA KLTVEEQVLE GEYRYVNSRL IMNSEEIAFY QGNKPEKQAL 

       310        320        330        340        350        360 
MGSFNNLVYH LRKTIMFRFT LGFVDNIVGK YITNIVGWVA CAKTFFDVNN EKFNEMDRNE 

       370        380        390        400        410        420 
LMQELYNNGR MMLKLSEALG RLALAGRDMT RLSGFTTRVD TLMKVLDDMK AGRFEKAQVA 

       430        440        450        460        470        480 
DESGEEGQRL MLKAGSGKLL AQDNMIKFDE VPLVTPNGDI LIESLSFEVP SGRNVLVCGP 

       490        500        510        520        530        540 
NGCGKSSLFR TLGELWPVMG GTLTKPAKGK LFYVPQRPYM TLGTLRDQVI YPDTSFDMKM 

       550        560        570        580        590        600 
KGMSDKDLEQ MLENVQLTNI LEREGGWSAV QDWMDVLSGG EKQRIAMARL FYHKPQFAIL 

       610        620        630        640        650        660 
DECTSAVSVD VEGAMYRLCR EMNITLFTVS HRKSLWKYHE YSLYMDGRGS YRFEQIDDQS 


DQFGS 

References and documentation are available.

Number of amino acids: 665

Molecular weight: 75259.50

Theoretical pI: 8.71

Amino acid composition: 
Ala (A)  36	  5.4%
Arg (R)  33	  5.0%
Asn (N)  31	  4.7%
Asp (D)  32	  4.8%
Cys (C)   7	  1.1%
Gln (Q)  22	  3.3%
Glu (E)  40	  6.0%
Gly (G)  52	  7.8%
His (H)   4	  0.6%
Ile (I)  34	  5.1%
Leu (L)  81	 12.2%
Lys (K)  46	  6.9%
Met (M)  31	  4.7%
Phe (F)  38	  5.7%
Pro (P)  20	  3.0%
Ser (S)  46	  6.9%
Thr (T)  33	  5.0%
Trp (W)   7	  1.1%
Tyr (Y)  28	  4.2%
Val (V)  44	  6.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 72
Total number of positively charged residues (Arg + Lys): 79

Atomic composition:

Carbon      C	      3399
Hydrogen    H	      5356
Nitrogen    N	       878
Oxygen      O	       970
Sulfur      S	        38

Formula: C3399H5356N878O970S38
Total number of atoms: 10641

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    80595
Abs 0.1% (=1 g/l)   1.071, assuming all pairs of Cys residues form cystines


Ext. coefficient    80220
Abs 0.1% (=1 g/l)   1.066, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 33.14
This classifies the protein as stable.



Aliphatic index: 92.05

Grand average of hydropathicity (GRAVY): -0.061