ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAVQQRKKKE GRKSDKNAPS VPQVDASLDK PLDIDAPPTI YSVNLKPEYG TAALNLSADF 

        70         80         90        100        110        120 
IRQEQALANK YLFFHPVILV VLTIGLLIYL TPRIVFPIRN TGSVAGWFYQ LARINKKVVL 

       130        140        150        160        170        180 
SGLVFTAIGA SFLFTLLSRV SDSYFKSKIN QLVGSKGEKV FGINLNDLVA RHETKDPVVN 

       190        200        210        220        230        240 
NTHIIVYRET PIALISLAPN MTLSTDENLV MSVTTVGCRR VYVKSGIIED LIDWAMLHSK 

       250        260        270        280        290        300 
NIRSSGKYGE TMKLLIDVYS FDSTLKEILK KKGFTYIQSI RVSENRLLGG LFGVKKELWG 

       310 
LQFHFKAEHK D 

References and documentation are available.

Number of amino acids: 311

Molecular weight: 34881.69

Theoretical pI: 9.62

Amino acid composition: 
Ala (A)  18	  5.8%
Arg (R)  14	  4.5%
Asn (N)  15	  4.8%
Asp (D)  15	  4.8%
Cys (C)   1	  0.3%
Gln (Q)   9	  2.9%
Glu (E)  13	  4.2%
Gly (G)  19	  6.1%
His (H)   6	  1.9%
Ile (I)  24	  7.7%
Leu (L)  36	 11.6%
Lys (K)  27	  8.7%
Met (M)   5	  1.6%
Phe (F)  15	  4.8%
Pro (P)  12	  3.9%
Ser (S)  24	  7.7%
Thr (T)  17	  5.5%
Trp (W)   3	  1.0%
Tyr (Y)  11	  3.5%
Val (V)  27	  8.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 28
Total number of positively charged residues (Arg + Lys): 41

Atomic composition:

Carbon      C	      1594
Hydrogen    H	      2551
Nitrogen    N	       419
Oxygen      O	       444
Sulfur      S	         6

Formula: C1594H2551N419O444S6
Total number of atoms: 5014

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    32890
Abs 0.1% (=1 g/l)   0.943, assuming all pairs of Cys residues form cystines


Ext. coefficient    32890
Abs 0.1% (=1 g/l)   0.943, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 28.80
This classifies the protein as stable.



Aliphatic index: 106.21

Grand average of hydropathicity (GRAVY): 0.001