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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAVSARLRTT AEDTSIAKST QDPIGDTEIS VANAKGSSDS NIKNSPGGNS VGQESELEHV

70 80 90 100 110 120
PEEDDSGDKE ADHEDSETAT AKKRKAQPLK NPKKSLKRGR VPAPLNLSDS NTNTHGGNIK

130 140 150 160 170 180
DGNLASSNSA HFPPVANQNV KSAPAQVTQH SKFQPRVQYL GKASSRQSIQ VNNSSNSYGK

190 200 210 220 230 240
PHMPSAGIMS AMNPYMPMNR YIMSPYYNPY GIPPPHMLNK PIMTPYVSYP YPMGPRTSIP

250 260 270 280 290 300
YAMQGGNARP YEENEYSASN YRNKRVNDSY DSPLSGTAST GKTRRSEEGS RNSSVGSSAN

310 320 330 340 350 360
AGPTQQRADL RPADMIPAEE YHFERDALLS ANTKARSAST STSTSTSTNR DRSSWHEAEP

370 380 390 400 410 420
NKDEEEGTDL AIEDGAVPTP TFTTFQRTSQ PQQQSPSLLQ GEIRLSSHIF AFEFPLSSSN

430 440 450
VDKKMFMSIC NKVWNESKEL TKKSSSHHRT GK


References and documentation are available.

Number of amino acids: 452 Molecular weight: 49356.19 Theoretical pI: 8.62
Amino acid composition: 
Ala (A) 36 8.0% Arg (R) 24 5.3% Asn (N) 33 7.3% Asp (D) 21 4.6% Cys (C) 1 0.2% Gln (Q) 19 4.2% Glu (E) 28 6.2% Gly (G) 26 5.8% His (H) 12 2.7% Ile (I) 16 3.5% Leu (L) 19 4.2% Lys (K) 28 6.2% Met (M) 14 3.1% Phe (F) 9 2.0% Pro (P) 37 8.2% Ser (S) 65 14.4% Thr (T) 30 6.6% Trp (W) 2 0.4% Tyr (Y) 16 3.5% Val (V) 16 3.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 49 Total number of positively charged residues (Arg + Lys): 52 Atomic composition: Carbon C 2105 Hydrogen H 3318 Nitrogen N 630 Oxygen O 714 Sulfur S 15 Formula: C2105H3318N630O714S15 Total number of atoms: 6782 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 34840 Abs 0.1% (=1 g/l) 0.706, assuming all pairs of Cys residues form cystines Ext. coefficient 34840 Abs 0.1% (=1 g/l) 0.706, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 59.78 This classifies the protein as unstable. Aliphatic index: 48.43 Grand average of hydropathicity (GRAVY): -0.982