ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAVSKVYARS VYDSRGNPTV EVELTTEKGV FRSIVPSGAS TGVHEALEMR DEDKSKWMGK 

        70         80         90        100        110        120 
GVMNAVNNVN NVIAAAFVKA NLDVKDQKAV DDFLLSLDGT ANKSKLGANA ILGVSMAAAR 

       130        140        150        160        170        180 
AAAAEKNVPL YQHLADLSKS KTSPYVLPVP FLNVLNGGSH AGGALALQEF MIAPTGAKTF 

       190        200        210        220        230        240 
AEAMRIGSEV YHNLKSLTKK RYGASAGNVG DEGGVAPNIQ TAEEALDLIV DAIKAAGHDG 

       250        260        270        280        290        300 
KVKIGLDCAS SEFFKDGKYD LDFKNPESDK SKWLTGVELA DMYHSLMKRY PIVSIEDPFA 

       310        320        330        340        350        360 
EDDWEAWSHF FKTAGIQIVA DDLTVTNPAR IATAIEKKAA DALLLKVNQI GTLSESIKAA 

       370        380        390        400        410        420 
QDSFAANWGV MVSHRSGETE DTFIADLVVG LRTGQIKTGA PARSERLAKL NQLLRIEEEL 

       430 
GDKAVYAGEN FHHGDKL 

References and documentation are available.

Number of amino acids: 437

Molecular weight: 46914.17

Theoretical pI: 5.67

Amino acid composition: 
Ala (A)  58	 13.3%
Arg (R)  14	  3.2%
Asn (N)  21	  4.8%
Asp (D)  30	  6.9%
Cys (C)   1	  0.2%
Gln (Q)   9	  2.1%
Glu (E)  28	  6.4%
Gly (G)  35	  8.0%
His (H)  10	  2.3%
Ile (I)  20	  4.6%
Leu (L)  38	  8.7%
Lys (K)  35	  8.0%
Met (M)  10	  2.3%
Phe (F)  15	  3.4%
Pro (P)  13	  3.0%
Ser (S)  30	  6.9%
Thr (T)  20	  4.6%
Trp (W)   5	  1.1%
Tyr (Y)  10	  2.3%
Val (V)  35	  8.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 58
Total number of positively charged residues (Arg + Lys): 49

Atomic composition:

Carbon      C	      2078
Hydrogen    H	      3303
Nitrogen    N	       569
Oxygen      O	       644
Sulfur      S	        11

Formula: C2078H3303N569O644S11
Total number of atoms: 6605

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    42400
Abs 0.1% (=1 g/l)   0.904, assuming all pairs of Cys residues form cystines


Ext. coefficient    42400
Abs 0.1% (=1 g/l)   0.904, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 29.56
This classifies the protein as stable.



Aliphatic index: 88.26

Grand average of hydropathicity (GRAVY): -0.184