ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAVVDVHRFA ESITCHAWSP DLSMVALCPN NTEVHIYKSL SQDHWERLHV LQKHDQIVSG 

        70         80         90        100        110        120 
IDWSSKSNKI VTVSHDRNSY VWSLEGAEWV PTLVILRLNR AALCVQWSPK ENKFAVGSGA 

       130        140        150        160        170        180 
KTVCICYYEQ ENNWWVSKLI RKRHESSVTS VAWHPNNVLL ATTSTDGKCR VFSTFIKGVD 

       190        200        210        220        230        240 
TKDSKAGSPA ETKFGEQILQ LDLSYSWAFG VKWSPSGNTL AYVGHSSMIY FVDDVGPSPL 

       250        260        270        280        290        300 
AQSVAFRDLP LRDVLFISEK MVIGVGYDSN PMVFAADDTG IWSFIRYIGE KKAASSGSSY 

       310        320        330        340        350        360 
SSQFSEAFGK FYGSQSKSTT ANDASDSRGG VHDNSITSIV PLGKGGSPKV MRFSTSGLDG 

       370 
KIAIWDLENM QQELGNQF 

References and documentation are available.

Number of amino acids: 378

Molecular weight: 41819.12

Theoretical pI: 6.60

Amino acid composition: 
Ala (A)  25	  6.6%
Arg (R)  13	  3.4%
Asn (N)  16	  4.2%
Asp (D)  22	  5.8%
Cys (C)   6	  1.6%
Gln (Q)  13	  3.4%
Glu (E)  16	  4.2%
Gly (G)  27	  7.1%
His (H)  11	  2.9%
Ile (I)  20	  5.3%
Leu (L)  25	  6.6%
Lys (K)  23	  6.1%
Met (M)   7	  1.9%
Phe (F)  16	  4.2%
Pro (P)  13	  3.4%
Ser (S)  50	 13.2%
Thr (T)  18	  4.8%
Trp (W)  13	  3.4%
Tyr (Y)  11	  2.9%
Val (V)  33	  8.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 38
Total number of positively charged residues (Arg + Lys): 36

Atomic composition:

Carbon      C	      1869
Hydrogen    H	      2864
Nitrogen    N	       504
Oxygen      O	       563
Sulfur      S	        13

Formula: C1869H2864N504O563S13
Total number of atoms: 5813

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    88265
Abs 0.1% (=1 g/l)   2.111, assuming all pairs of Cys residues form cystines


Ext. coefficient    87890
Abs 0.1% (=1 g/l)   2.102, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.60
This classifies the protein as stable.



Aliphatic index: 78.36

Grand average of hydropathicity (GRAVY): -0.229