ProtParam
User-provided sequence:
10 20 30 40 50 60
MAYASRFLSR SKQLQGGLVI LQQQHAIPVR AFAKEAARPT FKGDEMLKGV FFDIKNKFQA
70 80 90 100 110 120
AVDILRKEKI TLDPEDPAAV KQYANVMKTI RQKADMFSES QRIKHDIDTE TQDIPDARAY
130 140 150 160 170 180
LLKLQEIRTR RGLTDELGAE AMMFEALEKV EKDIKKPLLR SDKKGMDLLV AEFEKGNKKL
190 200 210 220 230 240
GIRKEDLPKY EENLELSMAK AQLDELKSDA VEAMESQKKK EEFQDEEMPD VKSLDIRNFI
References and
documentation are available.
Number of amino acids: 240
Molecular weight: 27596.84
Theoretical pI: 6.27
Total number of negatively charged residues (Asp + Glu): 45
Total number of positively charged residues (Arg + Lys): 44
Atomic composition:
Carbon C 1219
Hydrogen H 1991
Nitrogen N 335
Oxygen O 371
Sulfur S 10
Formula: C
1219H
1991N
335O
371S
10
Total number of atoms: 3926
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 5960
Abs 0.1% (=1 g/l) 0.216
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 43.71
This classifies the protein as unstable.
Aliphatic index: 83.42
Grand average of hydropathicity (GRAVY): -0.656