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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MCASPSTAPG FFNPRPQSGA ELSAFDIGLS RSMGLGVPPH SAWHEPPASL GGHLHAASAG

70 80 90 100 110 120
PGTTTGSVAT GGGGTTPSSV ASQQSAVIKQ DLSCPSLNQA GSGHHPGIKE DLSSSLPSAN

130 140 150 160 170 180
GGSAGGHHSG SGSGSGSGVN PGHGSDMLPL IKGHGQDMLT SIKGQPTGCG STTPSSQANS

190 200 210 220 230 240
SHSQSSNSGS QIDSKQNIEC VVCGDKSSGK HYGQFTCEGC KSFFKRSVRR NLTYSCRGSR

250 260 270 280 290 300
NCPIDQHHRN QCQYCRLKKC LKMGMRREAV QRGRVPPTQP GLAGMHGQYQ IANGDPMGIA

310 320 330 340 350 360
GFNGHSYLSS YISLLLRAEP YPTSRYGQCM QPNNIMGIDN ICELAARLLF SAVEWAKNIP

370 380 390 400 410 420
FFPELQVTDQ VALLRLVWSE LFVLNASQCS MPLHVAPLLA AAGLHASPMA ADRVVAFMDH

430 440 450 460 470 480
IRIFQEQVEK LKALHVDSAE YSCLKAIVLF TTDACGLSDV THIESLQEKS QCALEEYCRT

490 500 510 520 530 540
QYPNQPTRFG KLLLRLPSLR TVSSQVIEQL FFVRLVGKTP IETLIRDMLL SGNSFSWPYL


PSM


References and documentation are available.

Number of amino acids: 543 Molecular weight: 57987.75 Theoretical pI: 8.55
Amino acid composition: 
Ala (A) 40 7.4% Arg (R) 25 4.6% Asn (N) 19 3.5% Asp (D) 17 3.1% Cys (C) 19 3.5% Gln (Q) 32 5.9% Glu (E) 20 3.7% Gly (G) 55 10.1% His (H) 21 3.9% Ile (I) 22 4.1% Leu (L) 51 9.4% Lys (K) 19 3.5% Met (M) 15 2.8% Phe (F) 18 3.3% Pro (P) 36 6.6% Ser (S) 68 12.5% Thr (T) 24 4.4% Trp (W) 4 0.7% Tyr (Y) 12 2.2% Val (V) 26 4.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 37 Total number of positively charged residues (Arg + Lys): 44 Atomic composition: Carbon C 2518 Hydrogen H 3974 Nitrogen N 734 Oxygen O 773 Sulfur S 34 Formula: C2518H3974N734O773S34 Total number of atoms: 8033 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41005 Abs 0.1% (=1 g/l) 0.707, assuming all pairs of Cys residues form cystines Ext. coefficient 39880 Abs 0.1% (=1 g/l) 0.688, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 52.39 This classifies the protein as unstable. Aliphatic index: 73.68 Grand average of hydropathicity (GRAVY): -0.242