ProtParam
User-provided sequence:
10 20 30 40 50 60
MCCYCVCCTV SDFILYIVAF FFPPAAVLLR SGPCSSDFLL NVLLTLLGFL PGMLHAFYYI
70 80 90 100 110 120
TITSPLRNAE YVYYYQQGWV DSERNVPSNR PQNSQTPQNR PQQGSSARNV YPSVETPLLQ
130 140
GAAPHDNKQS LVESPPPYVP
References and
documentation are available.
Number of amino acids: 140
Molecular weight: 15672.92
Theoretical pI: 6.02
Total number of negatively charged residues (Asp + Glu): 8
Total number of positively charged residues (Arg + Lys): 7
Atomic composition:
Carbon C 712
Hydrogen H 1073
Nitrogen N 181
Oxygen O 203
Sulfur S 8
Formula: C
712H
1073N
181O
203S
8
Total number of atoms: 2177
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 20775
Abs 0.1% (=1 g/l) 1.326, assuming all pairs of Cys residues form cystines
Ext. coefficient 20400
Abs 0.1% (=1 g/l) 1.302, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 70.92
This classifies the protein as unstable.
Aliphatic index: 83.50
Grand average of hydropathicity (GRAVY): -0.022