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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MCLEPISLVV FGSLVFFFGL VKYFKRGERQ RTRGILQPEY KDKYYYSKEK GEEMGEVANV

70 80 90 100 110 120
NEIPVKIRNH KYPAKEHNLR VKDLLLNRNP KLSKISTAFF IAGEELEGNK YCDTNKDFRQ

130 140 150 160 170 180
NRYFYHLSGV DIPASAILFN CSTDKLTLFL PNIDEEDVIW SGMPLSLDEA MRVFDIDEAL

190 200 210 220 230 240
YISDLGKKFK ELQDFAIFTT DLDNVHDENI ARSLIPSDPN FFYAMDETRA IKDWYEIESI

250 260 270 280 290 300
RKACQISDKS HLAVMSALPI ELNELQIQAE FEYHATRQGG RSLGYDPICC SGPACGTLHY

310 320 330 340 350 360
VKNSEDIKGK HSILIDAGAE WRQYTSDITR CFPTSGKFTA EHREVYETVL DMQNQAMERI

370 380 390 400 410 420
KPGAKWDDLH ALTHKVLIKH FLSMGIFKKE FSEDEIFKRR ASCAFYPHGL GHMLGLDVHD

430 440 450 460 470 480
VGGNPNYDDP DPMFRYLRIR RPLKENMVIT NEPGCYFNQF LIKEFLEKHP ERLEVVDMSV

490 500 510 520 530
LKRYMYVGGV RIEDDILVTK DGYENLTGIT SDPDEIEKIV QKGLKKPRSG FHVIV


References and documentation are available.

Number of amino acids: 535 Molecular weight: 61753.56 Theoretical pI: 5.78
Amino acid composition: 
Ala (A) 26 4.9% Arg (R) 29 5.4% Asn (N) 23 4.3% Asp (D) 39 7.3% Cys (C) 10 1.9% Gln (Q) 13 2.4% Glu (E) 44 8.2% Gly (G) 33 6.2% His (H) 17 3.2% Ile (I) 39 7.3% Leu (L) 47 8.8% Lys (K) 41 7.7% Met (M) 14 2.6% Phe (F) 30 5.6% Pro (P) 24 4.5% Ser (S) 29 5.4% Thr (T) 20 3.7% Trp (W) 4 0.7% Tyr (Y) 24 4.5% Val (V) 29 5.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 83 Total number of positively charged residues (Arg + Lys): 70 Atomic composition: Carbon C 2777 Hydrogen H 4297 Nitrogen N 737 Oxygen O 811 Sulfur S 24 Formula: C2777H4297N737O811S24 Total number of atoms: 8646 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 58385 Abs 0.1% (=1 g/l) 0.945, assuming all pairs of Cys residues form cystines Ext. coefficient 57760 Abs 0.1% (=1 g/l) 0.935, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.86 This classifies the protein as stable. Aliphatic index: 83.27 Grand average of hydropathicity (GRAVY): -0.424