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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MCSTKVPNER TEKMNSGLIS TRHQVDPKKE LSRILRTDAA VKGIERKANS EKYLTLWPKA

70 80 90 100 110 120
VLEALDEAIK ENRWQSALKI FNLLRKQHWY EPRCKTYTKL FKVLGNCKQP DQASLLFEVM

130 140 150 160 170 180
LSEGLKPTID VYTSLISVYG KSELLDKAFS TLEYMKSVSD CKPDVFTFTV LISCCCKLGR

190 200 210 220 230 240
FDLVKSIVLE MSYLGVGCST VTYNTIIDGY GKAGMFEEME SVLADMIEDG DSLPDVCTLN

250 260 270 280 290 300
SIIGSYGNGR NMRKMESWYS RFQLMGVQPD ITTFNILILS FGKAGMYKKM CSVMDFMEKR

310 320 330 340 350 360
FFSLTTVTYN IVIETFGKAG RIEKMDDVFR KMKYQGVKPN SITYCSLVNA YSKAGLVVKI

370 380 390 400 410 420
DSVLRQIVNS DVVLDTPFFN CIINAYGQAG DLATMKELYI QMEERKCKPD KITFATMIKT

430 440
YTAHGIFDAV QELEKQMISS GENLDIL


References and documentation are available.

Number of amino acids: 447 Molecular weight: 50691.06 Theoretical pI: 8.40
Amino acid composition: 
Ala (A) 21 4.7% Arg (R) 17 3.8% Asn (N) 18 4.0% Asp (D) 25 5.6% Cys (C) 13 2.9% Gln (Q) 13 2.9% Glu (E) 28 6.3% Gly (G) 26 5.8% His (H) 3 0.7% Ile (I) 31 6.9% Leu (L) 41 9.2% Lys (K) 41 9.2% Met (M) 21 4.7% Phe (F) 20 4.5% Pro (P) 12 2.7% Ser (S) 34 7.6% Thr (T) 29 6.5% Trp (W) 4 0.9% Tyr (Y) 19 4.3% Val (V) 31 6.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 53 Total number of positively charged residues (Arg + Lys): 58 Atomic composition: Carbon C 2262 Hydrogen H 3608 Nitrogen N 580 Oxygen O 667 Sulfur S 34 Formula: C2262H3608N580O667S34 Total number of atoms: 7151 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 51060 Abs 0.1% (=1 g/l) 1.007, assuming all pairs of Cys residues form cystines Ext. coefficient 50310 Abs 0.1% (=1 g/l) 0.992, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 31.74 This classifies the protein as stable. Aliphatic index: 87.63 Grand average of hydropathicity (GRAVY): -0.120