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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDAIKKKMQA MKVDKDGALE RALVCEQEAR DANTRAEKAE EEARQLQKKI QTVENELDQT

70 80 90 100 110 120
QEALTLVTGK LEEKNKALQN AESEVAALNR RIQLLEEDLE RSEERLGSAT AKLSEASQAA

130 140 150 160 170 180
DESERARKIL ENRALADEER MDALENQLKE ARFLAEEADK KYDEVARKLA MVEADLERAE

190 200 210 220 230 240
ERAEQGENKI VELEEELRVV GNNLKSLEVS EEKANQREEE YKNQIKTLNT RLKEAEARAE

250 260 270 280 290 300
FAERSVQKLQ KEVDRLEDDL IVEKERYCMI GDSLDEAFVD LIKGLEPFWN PRNPKPPTPK

310 320 330 340 350 360
LPTPTPEELA AMEEARAAAE AAAAAEAEAA EAAAAAGEAG PDGAPAAPGE EKAPAKEPTP

370 380 390 400 410 420
PKEPTPPPPP PPPFEYSIDL PPEGAEVPYV KNYEPPPPGS EPEPVPAAEG EAAPAAEGAA

430 440 450 460 470 480
PPAEGAAPPA EGAVPPADGA APPAEGAAPA AEGAAPPADG AAPPAEAAAA PADAAAPAAE

490 500 510
AAPAEAPAAE ATAAEAPPAE AAPAEAAPAA AEGEAPPA


References and documentation are available.

Number of amino acids: 518 Molecular weight: 54585.35 Theoretical pI: 4.39
Amino acid composition: 
Ala (A) 121 23.4% Arg (R) 25 4.8% Asn (N) 16 3.1% Asp (D) 23 4.4% Cys (C) 2 0.4% Gln (Q) 16 3.1% Glu (E) 91 17.6% Gly (G) 22 4.2% His (H) 0 0.0% Ile (I) 10 1.9% Leu (L) 36 6.9% Lys (K) 33 6.4% Met (M) 7 1.4% Phe (F) 5 1.0% Pro (P) 59 11.4% Ser (S) 12 2.3% Thr (T) 14 2.7% Trp (W) 1 0.2% Tyr (Y) 6 1.2% Val (V) 19 3.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 114 Total number of positively charged residues (Arg + Lys): 58 Atomic composition: Carbon C 2355 Hydrogen H 3775 Nitrogen N 659 Oxygen O 811 Sulfur S 9 Formula: C2355H3775N659O811S9 Total number of atoms: 7609 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 14565 Abs 0.1% (=1 g/l) 0.267, assuming all pairs of Cys residues form cystines Ext. coefficient 14440 Abs 0.1% (=1 g/l) 0.265, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 52.11 This classifies the protein as unstable. Aliphatic index: 68.63 Grand average of hydropathicity (GRAVY): -0.718