ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDATTPLLTV ANSHPARNPK HTAWRAAVYD LQYILKASPL NFLLVFVPLG LIWGHFQLSH 

        70         80         90        100        110        120 
TLTFLFNFLA IIPLAAILAN ATEELADKAG NTIGGLLNAT FGNAVELIVS IIALKKGQVR 

       130        140        150        160        170        180 
IVQASMLGSL LSNLLLVLGL CFIFGGYNRV QQTFNQTAAQ TMSSLLAIAC ASLLIPAAFR 

       190        200        210        220        230        240 
ATLPHGKEDH FIDGKILELS RGTSIVILIV YVLFLYFQLG SHHALFEQQE EETDEVMSTI 

       250        260        270        280        290        300 
SRNPHHSLSV KSSLVILLGT TVIISFCADF LVGTIDNVVE STGLSKTFIG LIVIPIVGNA 

       310        320        330        340        350        360 
AEHVTSVLVA MKDKMDLALG VAIGSSLQVA LFVTPFMVLV GWMIDVPMTL NFSTFETATL 

       370        380        390        400        410 
FIAVFLSNYL ILDGESNWLE GVMSLAMYIL IAMAFFYYPD EKTLDSIGNS L 

References and documentation are available.

Number of amino acids: 411

Molecular weight: 44646.39

Theoretical pI: 5.39

Amino acid composition: 
Ala (A)  39	  9.5%
Arg (R)   7	  1.7%
Asn (N)  18	  4.4%
Asp (D)  14	  3.4%
Cys (C)   3	  0.7%
Gln (Q)  12	  2.9%
Glu (E)  16	  3.9%
Gly (G)  26	  6.3%
His (H)  11	  2.7%
Ile (I)  34	  8.3%
Leu (L)  63	 15.3%
Lys (K)  12	  2.9%
Met (M)  12	  2.9%
Phe (F)  26	  6.3%
Pro (P)  13	  3.2%
Ser (S)  31	  7.5%
Thr (T)  28	  6.8%
Trp (W)   4	  1.0%
Tyr (Y)   9	  2.2%
Val (V)  33	  8.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 30
Total number of positively charged residues (Arg + Lys): 19

Atomic composition:

Carbon      C	      2062
Hydrogen    H	      3250
Nitrogen    N	       500
Oxygen      O	       570
Sulfur      S	        15

Formula: C2062H3250N500O570S15
Total number of atoms: 6397

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    35535
Abs 0.1% (=1 g/l)   0.796, assuming all pairs of Cys residues form cystines


Ext. coefficient    35410
Abs 0.1% (=1 g/l)   0.793, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 27.54
This classifies the protein as stable.



Aliphatic index: 124.82

Grand average of hydropathicity (GRAVY): 0.705