ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDDDIAALVV DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH QGVMVGMGQK DSYVGDEAQS 

        70         80         90        100        110        120 
KRGILTLKYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPL NPKANREKMT 

       130        140        150        160        170        180 
QIMFETFNTP AMYVAIQAVL SLYASGRTTG IVMDSGDGVT HTVPIYEGYA LPHAILRLDL 

       190        200        210        220        230        240 
AGRDLTDYLM KILTERGYSF TTTAEREIVR DIKEKLCYVA LDFEQEMATA ASSSSLEKSY 

       250        260        270        280        290        300 
ELPDGQVITI GNERFRCPEA LFQPSFLGME SCGIHETTFN SIMKCDVDIR KDLYANTVLS 

       310        320        330        340        350        360 
GGTTMYPGIA DRMQKEITAL APSTMKIKII APPERKYSVW IGGSILASLS TFQEMWISKQ 

       370 
EYDESGPSIV HRKCF 

References and documentation are available.

Number of amino acids: 375

Molecular weight: 41737.72

Theoretical pI: 5.22

Amino acid composition: 
Ala (A)  29	  7.7%
Arg (R)  18	  4.8%
Asn (N)   9	  2.4%
Asp (D)  23	  6.1%
Cys (C)   6	  1.6%
Gln (Q)  11	  2.9%
Glu (E)  27	  7.2%
Gly (G)  28	  7.5%
His (H)   9	  2.4%
Ile (I)  28	  7.5%
Leu (L)  27	  7.2%
Lys (K)  19	  5.1%
Met (M)  17	  4.5%
Phe (F)  13	  3.5%
Pro (P)  19	  5.1%
Ser (S)  25	  6.7%
Thr (T)  26	  6.9%
Trp (W)   4	  1.1%
Tyr (Y)  15	  4.0%
Val (V)  22	  5.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 50
Total number of positively charged residues (Arg + Lys): 37

Atomic composition:

Carbon      C	      1850
Hydrogen    H	      2902
Nitrogen    N	       490
Oxygen      O	       562
Sulfur      S	        23

Formula: C1850H2902N490O562S23
Total number of atoms: 5827

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    44725
Abs 0.1% (=1 g/l)   1.072, assuming all pairs of Cys residues form cystines


Ext. coefficient    44350
Abs 0.1% (=1 g/l)   1.063, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.29
This classifies the protein as stable.



Aliphatic index: 81.95

Grand average of hydropathicity (GRAVY): -0.200