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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDDICSMAEN INRTLFNILG TEIDEINLNT NNLYNFIMES NLTKVEQHTL HKNISNNRLE

70 80 90 100 110 120
IYHHIKKEKS PKGKSSISPQ ARAFLEQVFR RKQSLNSKEK EEVAKKCGIT PLQVRVWFIN


KRMRSK


References and documentation are available.

Number of amino acids: 126 Molecular weight: 14803.06 Theoretical pI: 9.69
Amino acid composition: 
Ala (A) 4 3.2% Arg (R) 8 6.3% Asn (N) 14 11.1% Asp (D) 3 2.4% Cys (C) 2 1.6% Gln (Q) 5 4.0% Glu (E) 11 8.7% Gly (G) 3 2.4% His (H) 4 3.2% Ile (I) 12 9.5% Leu (L) 10 7.9% Lys (K) 14 11.1% Met (M) 4 3.2% Phe (F) 5 4.0% Pro (P) 3 2.4% Ser (S) 10 7.9% Thr (T) 6 4.8% Trp (W) 1 0.8% Tyr (Y) 2 1.6% Val (V) 5 4.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 14 Total number of positively charged residues (Arg + Lys): 22 Atomic composition: Carbon C 648 Hydrogen H 1058 Nitrogen N 192 Oxygen O 192 Sulfur S 6 Formula: C648H1058N192O192S6 Total number of atoms: 2096 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 8605 Abs 0.1% (=1 g/l) 0.581, assuming all pairs of Cys residues form cystines Ext. coefficient 8480 Abs 0.1% (=1 g/l) 0.573, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 63.51 This classifies the protein as unstable. Aliphatic index: 82.78 Grand average of hydropathicity (GRAVY): -0.744