ProtParam
User-provided sequence:
10 20 30 40 50 60
MDDICSMAEN INRTLFNILG TEIDEINLNT NNLYNFIMES NLTKVEQHTL HKNISNNRLE
70 80 90 100 110 120
IYHHIKKEKS PKGKSSISPQ ARAFLEQVFR RKQSLNSKEK EEVAKKCGIT PLQVRVWFIN
KRMRSK
References and
documentation are available.
Number of amino acids: 126
Molecular weight: 14803.06
Theoretical pI: 9.69
Total number of negatively charged residues (Asp + Glu): 14
Total number of positively charged residues (Arg + Lys): 22
Atomic composition:
Carbon C 648
Hydrogen H 1058
Nitrogen N 192
Oxygen O 192
Sulfur S 6
Formula: C
648H
1058N
192O
192S
6
Total number of atoms: 2096
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 8605
Abs 0.1% (=1 g/l) 0.581, assuming all pairs of Cys residues form cystines
Ext. coefficient 8480
Abs 0.1% (=1 g/l) 0.573, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 63.51
This classifies the protein as unstable.
Aliphatic index: 82.78
Grand average of hydropathicity (GRAVY): -0.744