ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDDSVSFIAK EASPAQYSHS LHERTHSEKQ KRDFTITEKQ DEVSGQTAEP RRTDSKSILQ 

        70         80         90        100        110        120 
RKCKEFFDSF KRQLPPDRNS ELESQEKNNL TKSIKSRHLV MISLGTGIGT GLLVGNGQVL 

       130        140        150        160        170        180 
GTAGPAGLVL GYGIASIMLY CIIQAAGELG LCYAGLTGNY TRYPSILVDP SLGFAVSVVY 

       190        200        210        220        230        240 
TIQWLTVLPL QLVTAAMTVK YWTSVNADIF VAVVFVFVII INLFGSRGYA EAEFIFNSCK 

       250        260        270        280        290        300 
ILMVIGFVIL AIIINCGGAG DRRYIGAEYW HNPGPFAHGF KGVCTVFCYA AFSYGGIEVL 

       310        320        330        340        350        360 
LLSAAEQENP TKSIPNACKK VVYRILLIYM LTTILVCFLV PYNSDELLGS SDSSGSHASP 

       370        380        390        400        410        420 
FVIAVASHGV KVVPHFINAV ILISVISVAN SSLYSGPRLL LSLAEQGVLP KCLAYVDRNG 

       430        440        450        460        470        480 
RPLLCFFVSL VFGCIGFVAT SDAEEQVFTW LLAISSLSQL FIWMSMSLSH IRFRDAMAKQ 

       490        500        510        520        530        540 
GRSMNEVGYK AQTGYWGSWL AVLIAIFFLV CQFWVAIAPV NEHGKLNVKV FFQNYLAMPI 

       550        560        570        580        590        600 
VLFAYFGHKI YFKSWSFWIP AEKIDLDSHR NIFVSPSLTE IDKVDDNDDL KEYENSESSE 

       610 
NPNSSRSRKF FKRMTNFWC 

References and documentation are available.

Number of amino acids: 619

Molecular weight: 68757.56

Theoretical pI: 7.85

Amino acid composition: 
Ala (A)  46	  7.4%
Arg (R)  23	  3.7%
Asn (N)  26	  4.2%
Asp (D)  22	  3.6%
Cys (C)  14	  2.3%
Gln (Q)  19	  3.1%
Glu (E)  29	  4.7%
Gly (G)  43	  6.9%
His (H)  13	  2.1%
Ile (I)  47	  7.6%
Leu (L)  60	  9.7%
Lys (K)  30	  4.8%
Met (M)  12	  1.9%
Phe (F)  40	  6.5%
Pro (P)  23	  3.7%
Ser (S)  60	  9.7%
Thr (T)  25	  4.0%
Trp (W)  11	  1.8%
Tyr (Y)  24	  3.9%
Val (V)  52	  8.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 51
Total number of positively charged residues (Arg + Lys): 53

Atomic composition:

Carbon      C	      3148
Hydrogen    H	      4854
Nitrogen    N	       800
Oxygen      O	       876
Sulfur      S	        26

Formula: C3148H4854N800O876S26
Total number of atoms: 9704

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    97135
Abs 0.1% (=1 g/l)   1.413, assuming all pairs of Cys residues form cystines


Ext. coefficient    96260
Abs 0.1% (=1 g/l)   1.400, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 36.47
This classifies the protein as stable.



Aliphatic index: 99.21

Grand average of hydropathicity (GRAVY): 0.245