ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDEDSVHGDS HLKTCVVLGG RGFIGRSLVS RLLRLGNWTV RVADSGHTLH LDESDSLLED 

        70         80         90        100        110        120 
ALSSGRASYH CVDVRDKPQI VKVTEGSYVV FYMGATDLRS HDYFDCYKVI VQGTRNVISA 

       130        140        150        160        170        180 
CRESGVRKLI YNSTADVVFD GSQPIRDGDE SLRRPLKFQS MLTDFKAQAE ALIKLANNRD 

       190        200        210        220        230        240 
GLLTCALRSS IVFGPGDTEF VPFLVNLAKS GYAKFILGSG ENISDFTYSE NVSHAHICAV 

       250        260        270        280        290        300 
KALDSQMEFV AGKEFFITNL KPVRFWDFVS HIVEGLGYPR PSIKLPVRLV LYVFSLLKWT 

       310        320        330        340        350        360 
HEKEGLGSNY DTAHQYALLA SSTRTFNCNA AKKHLGYTPV VTLEDGIAST LQWFSRDLEK 

       370        380        390        400        410        420 
SDDTIIQSTA DQLLGCGKVA DILLWRNEKK TFVSFLVLNL FYYWFFFSGN TFTSSAAQLL 

       430        440        450        460        470        480 
FIFAVALYGV SFVPSKIFGF QVNKIPPWRF EISESAVRDL SSDIVVVWNQ GVRSFKSLSS 

       490        500        510        520        530        540 
GGDWIKFFKI AGSLYLLKLI VSRSLAAFLF TVMSFSFTGF FIYEQYELEL YHLARIFVEC 

       550        560 
LTFIKRMVIP VSDASSKPMF M 

References and documentation are available.

Number of amino acids: 561

Molecular weight: 63033.42

Theoretical pI: 7.59

Amino acid composition: 
Ala (A)  35	  6.2%
Arg (R)  28	  5.0%
Asn (N)  17	  3.0%
Asp (D)  33	  5.9%
Cys (C)   9	  1.6%
Gln (Q)  14	  2.5%
Glu (E)  24	  4.3%
Gly (G)  37	  6.6%
His (H)  13	  2.3%
Ile (I)  30	  5.3%
Leu (L)  61	 10.9%
Lys (K)  30	  5.3%
Met (M)   8	  1.4%
Phe (F)  44	  7.8%
Pro (P)  15	  2.7%
Ser (S)  58	 10.3%
Thr (T)  27	  4.8%
Trp (W)   9	  1.6%
Tyr (Y)  20	  3.6%
Val (V)  49	  8.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 57
Total number of positively charged residues (Arg + Lys): 58

Atomic composition:

Carbon      C	      2885
Hydrogen    H	      4431
Nitrogen    N	       741
Oxygen      O	       812
Sulfur      S	        17

Formula: C2885H4431N741O812S17
Total number of atoms: 8886

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    79800
Abs 0.1% (=1 g/l)   1.266, assuming all pairs of Cys residues form cystines


Ext. coefficient    79300
Abs 0.1% (=1 g/l)   1.258, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.18
This classifies the protein as stable.



Aliphatic index: 94.83

Grand average of hydropathicity (GRAVY): 0.117