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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDEGVIAVSA MDAFEKLEKV GEGTYGKVYR AREKATGKIV ALKKTRLHED EEGVPSTTLR

70 80 90 100 110 120
EISILRMLAR DPHVVRLMDV KQGLSKEGKT VLYLVFEYMD TDVKKFIRSF RSTGKNIPTQ

130 140 150 160 170 180
TIKSLMYQLC KGMAFCHGHG ILHRDLKPHN LLMDPKTMRL KIADLGLARA FTLPMKKYTH

190 200 210 220 230 240
EILTLWYRAP EVLLGATHYS TAVDMWSVGC IFAELVTNQA IFQGDSELQQ LLHIFKLFGT

250 260 270 280 290 300
PNEEMWPGVS TLKNWHEYPQ WKPSTLSSAV PNLDEAGVDL LSKMLQYEPA KRISAKMAME

310
HPYFDDLPEK SSL


References and documentation are available.

Number of amino acids: 313 Molecular weight: 35593.45 Theoretical pI: 8.54
Amino acid composition: 
Ala (A) 21 6.7% Arg (R) 14 4.5% Asn (N) 6 1.9% Asp (D) 16 5.1% Cys (C) 3 1.0% Gln (Q) 9 2.9% Glu (E) 22 7.0% Gly (G) 19 6.1% His (H) 11 3.5% Ile (I) 14 4.5% Leu (L) 37 11.8% Lys (K) 27 8.6% Met (M) 15 4.8% Phe (F) 11 3.5% Pro (P) 15 4.8% Ser (S) 18 5.8% Thr (T) 20 6.4% Trp (W) 5 1.6% Tyr (Y) 11 3.5% Val (V) 19 6.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 38 Total number of positively charged residues (Arg + Lys): 41 Atomic composition: Carbon C 1603 Hydrogen H 2540 Nitrogen N 424 Oxygen O 454 Sulfur S 18 Formula: C1603H2540N424O454S18 Total number of atoms: 5039 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 44015 Abs 0.1% (=1 g/l) 1.237, assuming all pairs of Cys residues form cystines Ext. coefficient 43890 Abs 0.1% (=1 g/l) 1.233, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 31.99 This classifies the protein as stable. Aliphatic index: 87.86 Grand average of hydropathicity (GRAVY): -0.255