ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDEKTIKKSI LSSSNDEKII YKSRIKKFQK NHKFYIILLV FIAILQFISI AFFTRGFLLS 

        70         80         90        100        110        120 
RHVLDNISSQ NETSKLPPRF NKAVILVIDA LRFDFAIPVN ESHSNYNLNY HNNILSLYDS 

       130        140        150        160        170        180 
FASDKDASSL LLKFIADPPT TTLQRLKGLT TGSLPTFIDA GSNFDGTVIE EDNFLKQLHL 

       190        200        210        220        230        240 
ANKTVKFAGD DTWMALFHPF LSNDSFPLES LNVWDLDTVD NGVMDYFHDH LQQDKEWDVM 

       250        260        270        280        290        300 
IGHMLGIDHV GHKYGPDHFT MREKQIQVDQ FIDWILKSID DDTLLVILGD HGMDHTGNHG 

       310        320        330        340        350        360 
GDSIDELEST LFLYSKKPDM WRLKETSNYN IDNLGHDYRS VRQIDLVSSL ALLMGQPIPF 

       370        380        390        400        410        420 
NNLGWPIDEI ARNDREWSQF VNSAISQLQL YKDTMQIHHG NDEILEPLAK NISNTPPTSD 

       430        440        450        460        470        480 
PEKFVKLGHK YQKVFLQTCE ELWAKFDYYS IATGITLLAT SLVLLISITK LIPSIVVNQM 

       490        500        510        520        530        540 
VPEFVPGIII MVLVTNLCFH GIFYVYQQPS FVDQFWGTLL ATAIGIIIGC YITIFDRYNF 

       550        560        570        580        590        600 
IWIAMRLGET LADYWSRIAV MFMIIHALLF TSNSFTIWED RIVAFLLSTF GMLTLYEFVF 

       610        620        630        640        650        660 
LPKRQSTTAL LTATISEKEG TTSGVNPSTA NSNYLPLTRF ARLLGGYHSA VLIIFTRLAS 

       670        680        690        700        710        720 
MITICREEQG EYCIPTFNNQ NNSSWWVLGL CFLMIFILPA CITGYYNLTS SYQAAAPIWI 

       730        740        750        760        770        780 
NVFLKGILGL NFVYWSLTSL ENNSAVIAIP FLRDVTIFKF TLARIIAGFS LIASNVGWLM 

       790        800        810        820        830        840 
GPLCIKLNIH NTDVKSHEAT ILGYTNIYGS EFFLLVINVL ISILLFNKPL AQLSYFLMCN 

       850        860        870        880        890        900 
QLLSILEIID LLKLKENIIG PIALGLLSYQ HFFTTGHQAT IPSVQWDIGF MLSEKVTFPF 

       910        920        930        940        950        960 
TQIAIILNTF GPHILVSLSV ALLTLWSQPP DVLKPQTLLG RIVSNCGILL TYNTILCLSS 

       970        980        990       1000       1010 
FIWVTHFRRH LMVWKIFCPR FIFASLSLIV TQLVVTFGTI AFASGRLIKH INDIFWK 

References and documentation are available.

Number of amino acids: 1017

Molecular weight: 115634.49

Theoretical pI: 6.15

Amino acid composition: 
Ala (A)  50	  4.9%
Arg (R)  28	  2.8%
Asn (N)  56	  5.5%
Asp (D)  53	  5.2%
Cys (C)  12	  1.2%
Gln (Q)  35	  3.4%
Glu (E)  34	  3.3%
Gly (G)  52	  5.1%
His (H)  30	  2.9%
Ile (I) 107	 10.5%
Leu (L) 131	 12.9%
Lys (K)  46	  4.5%
Met (M)  22	  2.2%
Phe (F)  71	  7.0%
Pro (P)  38	  3.7%
Ser (S)  77	  7.6%
Thr (T)  68	  6.7%
Trp (W)  22	  2.2%
Tyr (Y)  32	  3.1%
Val (V)  53	  5.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 87
Total number of positively charged residues (Arg + Lys): 74

Atomic composition:

Carbon      C	      5360
Hydrogen    H	      8252
Nitrogen    N	      1320
Oxygen      O	      1460
Sulfur      S	        34

Formula: C5360H8252N1320O1460S34
Total number of atoms: 16426

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   169430
Abs 0.1% (=1 g/l)   1.465, assuming all pairs of Cys residues form cystines


Ext. coefficient   168680
Abs 0.1% (=1 g/l)   1.459, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.05
This classifies the protein as stable.



Aliphatic index: 111.30

Grand average of hydropathicity (GRAVY): 0.281