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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDFTAKIKEL ERELSETSDY KTLQKKTISL RSELNTLSHS LTSYEKEHFS NDIENVLKSI

70 80 90 100 110 120
NAKLSESKGK KRLFSFKQKN SSSAVHKNVE RTELANAPAY TTTLKKHYVL EKGDSAFENL

130 140 150 160 170 180
EFCTVTSTTD YSGNSALSGS LCFRNITKCV INLQRIFFQT GSIFITDCTD SIIFLRSPSD

190 200 210 220 230 240
KDFQIRLRDL KNCKILIEKL SPSIDCKQVV IIENCHKCIF NASTRDHLII QDFSNPFQSE

250 260
ETEDNSAFAF EDFDICNKDT MQLFRAYL


References and documentation are available.

Number of amino acids: 268 Molecular weight: 30708.78 Theoretical pI: 6.61
Amino acid composition: 
Ala (A) 12 4.5% Arg (R) 11 4.1% Asn (N) 17 6.3% Asp (D) 17 6.3% Cys (C) 9 3.4% Gln (Q) 9 3.4% Glu (E) 20 7.5% Gly (G) 5 1.9% His (H) 6 2.2% Ile (I) 21 7.8% Leu (L) 25 9.3% Lys (K) 25 9.3% Met (M) 2 0.7% Phe (F) 19 7.1% Pro (P) 4 1.5% Ser (S) 31 11.6% Thr (T) 21 7.8% Trp (W) 0 0.0% Tyr (Y) 6 2.2% Val (V) 8 3.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 37 Total number of positively charged residues (Arg + Lys): 36 Atomic composition: Carbon C 1354 Hydrogen H 2146 Nitrogen N 364 Oxygen O 427 Sulfur S 11 Formula: C1354H2146N364O427S11 Total number of atoms: 4302 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 9440 Abs 0.1% (=1 g/l) 0.307, assuming all pairs of Cys residues form cystines Ext. coefficient 8940 Abs 0.1% (=1 g/l) 0.291, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 46.99 This classifies the protein as unstable. Aliphatic index: 80.07 Grand average of hydropathicity (GRAVY): -0.441