ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDFYKLDEKL KELKRKRVDV SIKSRKLADR EIQEVSANRK PRVYSMEDVN DADESVGDTE 

        70         80         90        100        110        120 
SPEKEKAFHY TVQEYDAWER RHPQGKTGQS QRGGISYDQL AKLSYEKTLR NLATQTQNSS 

       130        140        150        160        170        180 
KQDSSADEED NKNVPKKGRI GKVQKDTKTG KITIADDDKL VNKLAVSLQS ESKKRYEARK 

       190        200        210 
RQMQNAKTLY GVESFINDKN KQFNEKLSRE SKGSE 

References and documentation are available.

Number of amino acids: 215

Molecular weight: 24802.61

Theoretical pI: 9.34

Amino acid composition: 
Ala (A)  12	  5.6%
Arg (R)  15	  7.0%
Asn (N)  11	  5.1%
Asp (D)  18	  8.4%
Cys (C)   0	  0.0%
Gln (Q)  14	  6.5%
Glu (E)  20	  9.3%
Gly (G)  10	  4.7%
His (H)   2	  0.9%
Ile (I)   7	  3.3%
Leu (L)  13	  6.0%
Lys (K)  31	 14.4%
Met (M)   3	  1.4%
Phe (F)   4	  1.9%
Pro (P)   4	  1.9%
Ser (S)  20	  9.3%
Thr (T)  10	  4.7%
Trp (W)   1	  0.5%
Tyr (Y)   8	  3.7%
Val (V)  12	  5.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 38
Total number of positively charged residues (Arg + Lys): 46

Atomic composition:

Carbon      C	      1064
Hydrogen    H	      1737
Nitrogen    N	       321
Oxygen      O	       355
Sulfur      S	         3

Formula: C1064H1737N321O355S3
Total number of atoms: 3480

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    17420
Abs 0.1% (=1 g/l)   0.702

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 45.18
This classifies the protein as unstable.



Aliphatic index: 58.05

Grand average of hydropathicity (GRAVY): -1.350