ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDGAKFENTV AFLPSEIFDC YNSTLPKNVF RSFVTWSCYE KFNSLEFRTW LLMWLPLIIA 

        70         80         90        100        110        120 
WKIRGKRHYL VIVTALMFEV LYFLWTYSYI FRERTLGKQV SQFAKEIITN TPGIDTEDWE 

       130        140        150        160        170        180 
RVAVNFNSYL YENKLWNTEY FFFDGSSCQE AFRKMLLEPF SLKKNDFANA KVPDGSVCYT 

       190        200        210        220        230        240 
EKALQVYFTQ IERKWHWINS EGFLHNKTTQ SVQFSKHGYG SKLLWAFKEV TIMNSRFAFF 

       250        260        270        280        290        300 
SIAYLNGLLT IPRLRNSLHI LYVCAVLSSM IIEYLIGIDK FRFKSMNLIH KLQFLSYITC 

       310        320        330        340        350        360 
GHEKSDATNW SQIAKRTNTY MFEQKIWNSP ILFSDGIDCE KFFKWYFSTP VSSQASLSVG 

       370        380 
STDFELWPYI KEAQSACNDV 

References and documentation are available.

Number of amino acids: 380

Molecular weight: 44803.58

Theoretical pI: 8.60

Amino acid composition: 
Ala (A)  19	  5.0%
Arg (R)  14	  3.7%
Asn (N)  21	  5.5%
Asp (D)  13	  3.4%
Cys (C)   8	  2.1%
Gln (Q)  12	  3.2%
Glu (E)  23	  6.1%
Gly (G)  14	  3.7%
His (H)   7	  1.8%
Ile (I)  26	  6.8%
Leu (L)  35	  9.2%
Lys (K)  27	  7.1%
Met (M)   8	  2.1%
Phe (F)  34	  8.9%
Pro (P)  10	  2.6%
Ser (S)  34	  8.9%
Thr (T)  23	  6.1%
Trp (W)  14	  3.7%
Tyr (Y)  19	  5.0%
Val (V)  19	  5.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 36
Total number of positively charged residues (Arg + Lys): 41

Atomic composition:

Carbon      C	      2084
Hydrogen    H	      3100
Nitrogen    N	       510
Oxygen      O	       562
Sulfur      S	        16

Formula: C2084H3100N510O562S16
Total number of atoms: 6272

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   105810
Abs 0.1% (=1 g/l)   2.362, assuming all pairs of Cys residues form cystines


Ext. coefficient   105310
Abs 0.1% (=1 g/l)   2.350, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 36.00
This classifies the protein as stable.



Aliphatic index: 82.11

Grand average of hydropathicity (GRAVY): -0.105