ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDGSMNLGNE PPGDGGGGGG LTRQGSIYSL TFDEFQSSVG KDFGSMNMDE LLKNIWSAEE 

        70         80         90        100        110        120 
TQAMASGVVP VLGGGQEGLQ LQRQGSLTLP RTLSQKTVDQ VWKDLSKVGS SGVGGSNLSQ 

       130        140        150        160        170        180 
VAQAQSQSQS QRQQTLGEVT LEEFLVRAGV VREEAQVAAR AQIAENNKGG YFGNDANTGF 

       190        200        210        220        230        240 
SVEFQQPSPR VVAAGVMGNL GAETANSLQV QGSSLPLNVN GARTTYQQSQ QQQPIMPKQP 

       250        260        270        280        290        300 
GFGYGTQMGQ LNSPGIRGGG LVGLGDQSLT NNVGFVQGAS AAIPGALGVG AVSPVTPLSS 

       310        320        330        340        350        360 
EGIGKSNGDS SSLSPSPYMF NGGVRGRKSG TVEKVVERRQ RRMIKNRESA ARSRARKQAY 

       370        380        390        400        410 
TVELEAEVAK LKEENDELQR KQARIMEMQK NQETEMRNLL QGGPKKKLRR TESGPW 

References and documentation are available.

Number of amino acids: 416

Molecular weight: 44165.29

Theoretical pI: 9.27

Amino acid composition: 
Ala (A)  29	  7.0%
Arg (R)  25	  6.0%
Asn (N)  22	  5.3%
Asp (D)  11	  2.6%
Cys (C)   0	  0.0%
Gln (Q)  41	  9.9%
Glu (E)  28	  6.7%
Gly (G)  58	 13.9%
His (H)   0	  0.0%
Ile (I)   9	  2.2%
Leu (L)  33	  7.9%
Lys (K)  19	  4.6%
Met (M)  13	  3.1%
Phe (F)  10	  2.4%
Pro (P)  18	  4.3%
Ser (S)  40	  9.6%
Thr (T)  19	  4.6%
Trp (W)   3	  0.7%
Tyr (Y)   6	  1.4%
Val (V)  32	  7.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 39
Total number of positively charged residues (Arg + Lys): 44

Atomic composition:

Carbon      C	      1884
Hydrogen    H	      3060
Nitrogen    N	       576
Oxygen      O	       623
Sulfur      S	        13

Formula: C1884H3060N576O623S13
Total number of atoms: 6156

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    25440
Abs 0.1% (=1 g/l)   0.576

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 52.64
This classifies the protein as unstable.



Aliphatic index: 68.65

Grand average of hydropathicity (GRAVY): -0.592