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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDHQITTASD FTTTSIPSLY QLDTLLRCHI CKDFLKVPVL TPCGHTFCSL CIRTHLNNQP

70 80 90 100 110 120
NCPLCLFEFR ESLLRSEFLV SEIIQSYTSL RSSLLDALRI PKPTPVPENE EVPGPENSSW

130 140 150 160 170 180
IELISESESD SVNAADDDLQ IVATSERKLA KRSMTDILPL SSKPSKRNFA MFRSERIKKK

190 200 210 220 230 240
SKPNEQMAQC PICQQFYPLK ALEKTHLDEC LTLQSLGKKP KISTTFPTES NPHNKSSSRF

250 260 270 280 290 300
KVRTPEVDKS SCGETSHVDK YLNSMMSAEH QRLPKINFTS MTQSQIKQKL SSLGLSTNGT

310 320 330 340 350 360
RQNMIKRYNH YEMLWNSNFC DSLEPVDEAE LKRQLLSWDV SHNKTPQNSS NKGGISKLMI

370 380 390 400 410 420
MKSNGKSSSY RKLLENFKND KFNRKGWMVM FRKDFARLIR EAKMKIKTGS SDSSGSVGHS

430 440 450 460 470 480
NDGDGVEKVQ SDQGTEDQQM EKDQDTVINE DRVAGERNLP NEDSTDADLS RELMDLNEYS


KDPPGNN


References and documentation are available.

Number of amino acids: 487 Molecular weight: 55230.36 Theoretical pI: 7.53
Amino acid composition: 
Ala (A) 15 3.1% Arg (R) 25 5.1% Asn (N) 31 6.4% Asp (D) 31 6.4% Cys (C) 12 2.5% Gln (Q) 22 4.5% Glu (E) 34 7.0% Gly (G) 18 3.7% His (H) 11 2.3% Ile (I) 22 4.5% Leu (L) 46 9.4% Lys (K) 41 8.4% Met (M) 16 3.3% Phe (F) 17 3.5% Pro (P) 26 5.3% Ser (S) 61 12.5% Thr (T) 29 6.0% Trp (W) 4 0.8% Tyr (Y) 8 1.6% Val (V) 18 3.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 65 Total number of positively charged residues (Arg + Lys): 66 Atomic composition: Carbon C 2383 Hydrogen H 3824 Nitrogen N 682 Oxygen O 769 Sulfur S 28 Formula: C2383H3824N682O769S28 Total number of atoms: 7686 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 34670 Abs 0.1% (=1 g/l) 0.628, assuming all pairs of Cys residues form cystines Ext. coefficient 33920 Abs 0.1% (=1 g/l) 0.614, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 48.70 This classifies the protein as unstable. Aliphatic index: 68.25 Grand average of hydropathicity (GRAVY): -0.756