ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDIDEQIIQD YSNSKLDVVQ IDGLVVLKII KQCKEYLPEL VPGQLLGLDI GTSLEVSNCF 

        70         80         90        100        110        120 
PFPPRDQEDE NSESIADYQL EMMRFLREVN IDSNTVGWYT PTYLNSFFNE SVIETQYNYQ 

       130        140        150        160        170        180 
ATINQKCVVI VYDPIKTSQG TLSLKCYRLT QSFMELFKDQ SFSRERLDQA NLSFNDIFEQ 

       190        200        210        220        230        240 
IPIKIHNSQL INALLYEFDG ASNNLTNSFD RLNISNNIYL EKVVEGMTDC LESLNQELNK 

       250        260        270        280        290        300 
VYINQRNIQT QKTNYIQQKF LEGQKVDEDE LASMIKPLNP PSKLTSLLLT NQINNYTDQI 

       310 
HSFSGNSLTK LSLLKDLQK 

References and documentation are available.

Number of amino acids: 319

Molecular weight: 36785.57

Theoretical pI: 4.59

Amino acid composition: 
Ala (A)   6	  1.9%
Arg (R)   8	  2.5%
Asn (N)  29	  9.1%
Asp (D)  21	  6.6%
Cys (C)   5	  1.6%
Gln (Q)  26	  8.2%
Glu (E)  22	  6.9%
Gly (G)  10	  3.1%
His (H)   2	  0.6%
Ile (I)  26	  8.2%
Leu (L)  39	 12.2%
Lys (K)  19	  6.0%
Met (M)   6	  1.9%
Phe (F)  14	  4.4%
Pro (P)  11	  3.4%
Ser (S)  27	  8.5%
Thr (T)  17	  5.3%
Trp (W)   1	  0.3%
Tyr (Y)  14	  4.4%
Val (V)  16	  5.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 43
Total number of positively charged residues (Arg + Lys): 27

Atomic composition:

Carbon      C	      1634
Hydrogen    H	      2572
Nitrogen    N	       422
Oxygen      O	       519
Sulfur      S	        11

Formula: C1634H2572N422O519S11
Total number of atoms: 5158

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    26610
Abs 0.1% (=1 g/l)   0.723, assuming all pairs of Cys residues form cystines


Ext. coefficient    26360
Abs 0.1% (=1 g/l)   0.717, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 28.16
This classifies the protein as stable.



Aliphatic index: 95.89

Grand average of hydropathicity (GRAVY): -0.399