ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDKEVSELVV LQLIHTLISN KNEELVRNGG GINMIGNNLR ISLVKLTNEI QNNLLINELT 

        70         80         90        100        110        120 
NLRRQSNVAN GNRKLGINDI LTIVKNLFPE YRTTLNDGQL SLHGLEMHDI EKLLDEKYDR 

       130        140        150        160        170        180 
FKKTQVEQIR MMEDEILKNG IKTGASQLQP HANAGKSGSA GTSATITTTT PHMAHSMDPK 

       190        200        210        220        230        240 
REKLLKLYRD TVLNKLESKT GNFQKLFKSP DGSIIKNEIN YEDIKNETPG SVHELQLILQ 

       250        260        270 
KSITDGVMRK VIGTDDWKLA RQVQFELDDT VQFMRRALE 

References and documentation are available.

Number of amino acids: 279

Molecular weight: 31644.24

Theoretical pI: 7.88

Amino acid composition: 
Ala (A)   9	  3.2%
Arg (R)  14	  5.0%
Asn (N)  24	  8.6%
Asp (D)  16	  5.7%
Cys (C)   0	  0.0%
Gln (Q)  14	  5.0%
Glu (E)  21	  7.5%
Gly (G)  18	  6.5%
His (H)   7	  2.5%
Ile (I)  22	  7.9%
Leu (L)  35	 12.5%
Lys (K)  24	  8.6%
Met (M)   9	  3.2%
Phe (F)   6	  2.2%
Pro (P)   6	  2.2%
Ser (S)  15	  5.4%
Thr (T)  20	  7.2%
Trp (W)   1	  0.4%
Tyr (Y)   4	  1.4%
Val (V)  14	  5.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 37
Total number of positively charged residues (Arg + Lys): 38

Atomic composition:

Carbon      C	      1381
Hydrogen    H	      2280
Nitrogen    N	       398
Oxygen      O	       431
Sulfur      S	         9

Formula: C1381H2280N398O431S9
Total number of atoms: 4499

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    11460
Abs 0.1% (=1 g/l)   0.362

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 26.59
This classifies the protein as stable.



Aliphatic index: 97.46

Grand average of hydropathicity (GRAVY): -0.536