ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDLKTSYKGI SLNPIYAGSS AVATVSENGK ILATPVLDEI NIIDLTPGSR KILHKISNED 

        70         80         90        100        110        120 
EQEITALKLT PDGQYLTYVS QAQLLKIFHL KTGKVVRSMK ISSPSYILDA DSTSTLLAVG 

       130        140        150        160        170        180 
GTDGSIIVVD IENGYITHSF KGHGGTISSL KFYGQLNSKI WLLASGDTNG MVKVWDLVKR 

       190        200        210        220        230        240 
KCLHTLQEHT SAVRGLDIIE VPDNDEPSLN LLSGGRDDII NLWDFNMKKK CKLLKTLPVN 

       250        260        270        280        290        300 
QQVESCGFLK DGDGKRIIYT AGGDAIFQLI DSESGSVLKR TNKPIEELFI IGVLPILSNS 

       310        320        330        340        350        360 
QMFLVLSDQT LQLINVEEDL KNDEDTIQVT SSIAGNHGII ADMRYVGPEL NKLALATNSP 

       370        380        390        400        410        420 
SLRIIPVPDL SGPEASLPLD VEIYEGHEDL LNSLDATEDG LWIATASKDN TAIVWRYNEN 

       430        440        450        460        470        480 
SCKFDIYAKY IGHSAAVTAV GLPNIVSKGY PEFLLTASND LTIKKWIIPK PTASMDVQII 

       490        500        510        520        530        540 
KVSEYTRHAH EKDINALSVS PNDSIFATAS YDKTCKIWNL ENGELEATLA NHKRGLWDVS 

       550        560        570        580        590        600 
FCQYDKLLAT SSGDKTVKIW SLDTFSVMKT LEGHTNAVQR CSFINKQKQL ISCGADGLIK 

       610        620        630        640        650        660 
IWDCSSGECL KTLDGHNNRL WALSTMNDGD MIVSADADGV FQFWKDCTEQ EIEEEQEKAK 

       670        680        690        700        710        720 
LQVEQEQSLQ NYMSKGDWTN AFLLAMTLDH PMRLFNVLKR ALGESRSRQD TEEGKIEVIF 

       730        740        750        760        770        780 
NEELDQAISI LNDEQLILLM KRCRDWNTNA KTHTIAQRTI RCILMHHNIA KLSEIPGMVK 

       790        800        810 
IVDAIIPYTQ RHFTRVDNLV EQSYILDYAL VEMDKLF 

References and documentation are available.

Number of amino acids: 817

Molecular weight: 91031.87

Theoretical pI: 5.22

Amino acid composition: 
Ala (A)  49	  6.0%
Arg (R)  24	  2.9%
Asn (N)  44	  5.4%
Asp (D)  60	  7.3%
Cys (C)  13	  1.6%
Gln (Q)  31	  3.8%
Glu (E)  49	  6.0%
Gly (G)  49	  6.0%
His (H)  19	  2.3%
Ile (I)  72	  8.8%
Leu (L)  90	 11.0%
Lys (K)  58	  7.1%
Met (M)  17	  2.1%
Phe (F)  21	  2.6%
Pro (P)  24	  2.9%
Ser (S)  66	  8.1%
Thr (T)  51	  6.2%
Trp (W)  14	  1.7%
Tyr (Y)  21	  2.6%
Val (V)  45	  5.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 109
Total number of positively charged residues (Arg + Lys): 82

Atomic composition:

Carbon      C	      4042
Hydrogen    H	      6444
Nitrogen    N	      1074
Oxygen      O	      1249
Sulfur      S	        30

Formula: C4042H6444N1074O1249S30
Total number of atoms: 12839

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   109040
Abs 0.1% (=1 g/l)   1.198, assuming all pairs of Cys residues form cystines


Ext. coefficient   108290
Abs 0.1% (=1 g/l)   1.190, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 38.36
This classifies the protein as stable.



Aliphatic index: 99.30

Grand average of hydropathicity (GRAVY): -0.194