ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDLLAASVES TLKNLQDKRN FLSEQREHYI DIRSRLVRFI NDNDDGEEEG EGQGMVFGDI 

        70         80         90        100        110        120 
IISTSKIYLS LGYEYYVEKT KEEAITFVDD KLKLMEDAIE QFNLKIEEAK KTLDNLNHME 

       130        140        150        160        170        180 
DGNGIEEDEA NNDEDFLPSM EIREELDDEG NVISSSVTPT TKQPSQSNSK KEQTPAVGPK 

       190        200        210        220        230        240 
EKGLAKEKKS KSFEENLKGK LLKRNDEVKK KVQPSKVDTE NVYTFADLVQ QMDQQDELED 

       250        260        270        280        290        300 
GYIETDEINY DYDAFENSNF KVNDNYEEDD EDEDEEEYLN HSIIPGFEAQ SSFLQQIQRL 

       310        320        330        340        350        360 
RAQKQSQDHE REEGDVNKSL KPILKKSSFA ENSDKKQKKK QVGFASSLEI HEVENLKEEN 

       370        380        390        400        410        420 
KRQMQSFAVP MYETQESTGI ANKMTSDEFD GDLFAKMLGV QEADEVHEKY KEELINQERL 

       430        440        450        460        470        480 
EGEASRSNRR TRVSRFRKDR ASKKENTLST FKQETTRSVE NEVVEKEPVV GDIIEKEPVV 

       490        500        510        520        530        540 
GDVIEKEPVV GDVIEKEPAV TDIVEREPAV NDIVERKPVV GDIIEKEPTI NDIVEKEPEI 

       550        560        570        580        590        600 
NSKSEFETPF KKKKLKSLQK PRSSKSMKKK FDPKILENIS DDDYDDDDDG NKKLLSNKSK 

       610        620        630        640        650        660 
NNTDEQDKFP SKIQEVSRSM AKTGATVGSE PVRITNVDYH ALGGNLDDMV KAYSLGLYDD 

       670        680        690        700        710        720 
DLEEDPGTIV EKLEDFKEYN KQVELLRDEI RDFQLENKPV TMEEEENDGN VMNDIIEHEF 

       730        740        750        760        770        780 
PESYTNDEDE VALHPGRLQE EVAIEYRRLK EATASKWQSS SPAAHTEGEL EPIDKFGNPV 

       790 
KTSRFRSQRL HMDSKP 

References and documentation are available.

Number of amino acids: 796

Molecular weight: 91421.88

Theoretical pI: 4.63

Amino acid composition: 
Ala (A)  32	  4.0%
Arg (R)  33	  4.1%
Asn (N)  47	  5.9%
Asp (D)  73	  9.2%
Cys (C)   0	  0.0%
Gln (Q)  35	  4.4%
Glu (E) 114	 14.3%
Gly (G)  35	  4.4%
His (H)  11	  1.4%
Ile (I)  43	  5.4%
Leu (L)  52	  6.5%
Lys (K)  83	 10.4%
Met (M)  16	  2.0%
Phe (F)  28	  3.5%
Pro (P)  30	  3.8%
Ser (S)  59	  7.4%
Thr (T)  33	  4.1%
Trp (W)   1	  0.1%
Tyr (Y)  20	  2.5%
Val (V)  51	  6.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 187
Total number of positively charged residues (Arg + Lys): 116

Atomic composition:

Carbon      C	      3960
Hydrogen    H	      6287
Nitrogen    N	      1083
Oxygen      O	      1365
Sulfur      S	        16

Formula: C3960H6287N1083O1365S16
Total number of atoms: 12711

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    35300
Abs 0.1% (=1 g/l)   0.386

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 53.52
This classifies the protein as unstable.



Aliphatic index: 69.15

Grand average of hydropathicity (GRAVY): -1.051