ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDLTISNELT GEIYGPIEVS EDMALTDLIA LLQADCGFDK TKHDLYYNMD ILDSNRTQSL 

        70         80         90        100        110        120 
KELGLKTDDL LLIRGKISNS IQTDAATLSD EAFIEQFRQE LLNNQMLRSQ LILQIPGLND 

       130        140        150        160        170        180 
LVNDPLLFRE RLGPLILQRR YGGYNTAMNP FGIPQDEYTR LMANPDDPDN KKRIAELLDQ 

       190        200        210        220        230        240 
QAIDEQLRNA IEYTPEMFTQ VPMLYINIEI NNYPVKAFVD TGAQTTIMST RLAKKTGLSR 

       250        260        270        280        290        300 
MIDKRFIGEA RGVGTGKIIG RIHQAQVKIE TQYIPCSFTV LDTDIDVLIG LDMLKRHLAC 

       310        320        330        340        350        360 
VDLKENVLRI AEVETSFLSE AEIPKSFQEG LPAPTSVTTS SDKPLTPTKT SSTLPPQPGA 

       370        380        390        400        410        420 
VPALAPRTGM GPTPTGRSTA GATTATGRTF PEQTIKQLMD LGFPRDAVVK ALKQTNGNAE 


FAASLLFQ 

References and documentation are available.

Number of amino acids: 428

Molecular weight: 47354.17

Theoretical pI: 4.96

Amino acid composition: 
Ala (A)  31	  7.2%
Arg (R)  22	  5.1%
Asn (N)  19	  4.4%
Asp (D)  30	  7.0%
Cys (C)   3	  0.7%
Gln (Q)  24	  5.6%
Glu (E)  25	  5.8%
Gly (G)  27	  6.3%
His (H)   3	  0.7%
Ile (I)  32	  7.5%
Leu (L)  51	 11.9%
Lys (K)  21	  4.9%
Met (M)  13	  3.0%
Phe (F)  15	  3.5%
Pro (P)  26	  6.1%
Ser (S)  21	  4.9%
Thr (T)  39	  9.1%
Trp (W)   0	  0.0%
Tyr (Y)  10	  2.3%
Val (V)  16	  3.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 55
Total number of positively charged residues (Arg + Lys): 43

Atomic composition:

Carbon      C	      2090
Hydrogen    H	      3380
Nitrogen    N	       564
Oxygen      O	       652
Sulfur      S	        16

Formula: C2090H3380N564O652S16
Total number of atoms: 6702

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    15025
Abs 0.1% (=1 g/l)   0.317, assuming all pairs of Cys residues form cystines


Ext. coefficient    14900
Abs 0.1% (=1 g/l)   0.315, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 37.55
This classifies the protein as stable.



Aliphatic index: 93.71

Grand average of hydropathicity (GRAVY): -0.252