ProtParam
User-provided sequence:
10 20 30 40 50 60
MDLVNHLEDR LLFAVPKKGR LYESCVNVLK GSDIKFRRNP RLDIALVQNL PIALVFLPAA
70 80 90 100 110 120
DIPRFVGTGR VHLGITGQDQ IAEARLRIGD KLKIEELVDL QFGGCKLQVQ VPESGDITSV
130 140 150 160 170 180
DQLVGRRIVT SFEYLVAEYF DKVEKKAKSE GKVDSGIKTE ISFVSGSVEA SCALGIADAV
190 200 210 220 230 240
VDLVESGETM RASGLKPIET VMSTSAVLVR SSNCSSELEP LLQTIITRIR GYIIAQQYVL
250 260 270 280 290 300
VNYNVNREHL PVVLKITPGK RAPTITTLDE PGWVAVSSMV VKKEVAQVMD KLSQNHAHDI
310
LVLSIDNSRP
References and
documentation are available.
Number of amino acids: 310
Molecular weight: 34029.43
Theoretical pI: 6.55
Total number of negatively charged residues (Asp + Glu): 38
Total number of positively charged residues (Arg + Lys): 37
Atomic composition:
Carbon C 1512
Hydrogen H 2486
Nitrogen N 416
Oxygen O 453
Sulfur S 9
Formula: C
1512H
2486N
416O
453S
9
Total number of atoms: 4876
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 14690
Abs 0.1% (=1 g/l) 0.432, assuming all pairs of Cys residues form cystines
Ext. coefficient 14440
Abs 0.1% (=1 g/l) 0.424, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 31.29
This classifies the protein as stable.
Aliphatic index: 111.52
Grand average of hydropathicity (GRAVY): 0.047