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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDMKGTYLVT VILLVSTLSV GMCSNGWIRA HATYYGVNDS PASLGGACGY DNPYHAGFGA

70 80 90 100 110 120
HTAALSGELF RSGESCGGCY QVRCDFPADP KWCLRGAAVT VTATNFCPTN NNNGWCNLPR

130 140 150 160 170 180
HHFDMSSPAF FRIARRGNEG IVPVFYRRVG CKRRGGVRFT MRGQGNFNMV MISNVGGGGS

190 200 210 220 230 240
VRSVAVRGSK GKTWLQMTRN WGANWQSSGD LRGQRLSFKV TLTDSKTQTF LNVVPSSWWF

250
GQTFSSRGRQ FV


References and documentation are available.

Number of amino acids: 252 Molecular weight: 27617.36 Theoretical pI: 10.06
Amino acid composition: 
Ala (A) 16 6.3% Arg (R) 21 8.3% Asn (N) 16 6.3% Asp (D) 8 3.2% Cys (C) 9 3.6% Gln (Q) 8 3.2% Glu (E) 3 1.2% Gly (G) 33 13.1% His (H) 5 2.0% Ile (I) 5 2.0% Leu (L) 14 5.6% Lys (K) 7 2.8% Met (M) 8 3.2% Phe (F) 15 6.0% Pro (P) 9 3.6% Ser (S) 22 8.7% Thr (T) 17 6.7% Trp (W) 8 3.2% Tyr (Y) 7 2.8% Val (V) 21 8.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 11 Total number of positively charged residues (Arg + Lys): 28 Atomic composition: Carbon C 1214 Hydrogen H 1858 Nitrogen N 364 Oxygen O 345 Sulfur S 17 Formula: C1214H1858N364O345S17 Total number of atoms: 3798 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 54930 Abs 0.1% (=1 g/l) 1.989, assuming all pairs of Cys residues form cystines Ext. coefficient 54430 Abs 0.1% (=1 g/l) 1.971, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.76 This classifies the protein as unstable. Aliphatic index: 59.92 Grand average of hydropathicity (GRAVY): -0.243