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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDNGTDSSTS KFVPEYRRTN FKNKGRFSAD ELRRRRDTQQ VELRKAKRDE ALAKRRNFIP

70 80 90 100 110 120
PTDGADSDEE DESSVSADQQ FYSQLQQELP QMTQQLNSDD MQEQLSATVK FRQILSREHR

130 140 150 160 170 180
PPIDVVIQAG VVPRLVEFMR ENQPEMLQLE AAWALTNIAS GTSAQTKVVV DADAVPLFIQ

190 200 210 220 230 240
LLYTGSVEVK EQAIWALGNV AGDSTDYRDY VLQCNAMEPI LGLFNSNKPS LIRTATWTLS

250 260 270 280 290 300
NLCRGKKPQP DWSVVSQALP TLAKLIYSMD TETLVDACWA ISYLSDGPQE AIQAVIDVRI

310 320 330 340 350 360
PKRLVELLSH ESTLVQTPAL RAVGNIVTGN DLQTQVVINA GVLPALRLLL SSPKENIKKE

370 380 390 400 410 420
ACWTISNITA GNTEQIQAVI DANLIPPLVK LLEVAEYKTK KEACWAISNA SSGGLQRPDI

430 440 450 460 470 480
IRYLVSQGCI KPLCDLLEIA DNRIIEVTLD ALENILKMGE ADKEARGLNI NENADFIEKA

490 500 510 520 530 540
GGMEKIFNCQ QNENDKIYEK AYKIIETYFG EEEDAVDETM APQNAGNTFG FGSNVNQQFN


FN


References and documentation are available.

Number of amino acids: 542 Molecular weight: 60441.36 Theoretical pI: 4.80
Amino acid composition: 
Ala (A) 48 8.9% Arg (R) 27 5.0% Asn (N) 34 6.3% Asp (D) 34 6.3% Cys (C) 8 1.5% Gln (Q) 36 6.6% Glu (E) 42 7.7% Gly (G) 26 4.8% His (H) 2 0.4% Ile (I) 36 6.6% Leu (L) 51 9.4% Lys (K) 29 5.4% Met (M) 10 1.8% Phe (F) 16 3.0% Pro (P) 24 4.4% Ser (S) 34 6.3% Thr (T) 30 5.5% Trp (W) 7 1.3% Tyr (Y) 12 2.2% Val (V) 36 6.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 76 Total number of positively charged residues (Arg + Lys): 56 Atomic composition: Carbon C 2653 Hydrogen H 4243 Nitrogen N 733 Oxygen O 841 Sulfur S 18 Formula: C2653H4243N733O841S18 Total number of atoms: 8488 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 56880 Abs 0.1% (=1 g/l) 0.941, assuming all pairs of Cys residues form cystines Ext. coefficient 56380 Abs 0.1% (=1 g/l) 0.933, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.36 This classifies the protein as unstable. Aliphatic index: 90.72 Grand average of hydropathicity (GRAVY): -0.357