ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDNLQVSDIE TALQCISSTA SQDDKNKALQ FLEQFQRSTV AWSICNEILS KEDPTNALLE 

        70         80         90        100        110        120 
LNIFAAQTLR NKVTYDLSQL ENNLPQFKDS LLTLLLSHNQ KLIITQLNVA LARLAIQFLE 

       130        140        150        160        170        180 
WQNPIFEIIS LLNSSPSILL NFLRILPEET LDIASTSLTE VEFNSRIHEL IDPIAEDVLK 

       190        200        210        220        230        240 
FLVSCIDLLQ NTDGNSSSSI SLEQILRCLN SWSYEFPVEQ LLTVQPLINL VFETISNGNE 

       250        260        270        280        290        300 
SDMEAFDSAI DCLCVILRES RDTTNEQLIS ALFHQLMLLQ EKLLPTLFTD HPLNDEYDDD 

       310        320        330        340        350        360 
LLEGMTRLFV EAGEAWSVVI SKNPDFFKPM VLVLLMLTCK NEDLDVVSYT FPFWFNFKQS 

       370        380        390        400        410        420 
LVLPRYQESR KAYSDIFVKL INGIITHLQY PSGQFSSKEE EDKFKDFRYH MGDVLKDCTA 

       430        440        450        460        470        480 
VVGTSEALSQ PLIRIKSAIE NNNSWQIMEA PLFSLRTMAK EISLTENTIL PEIIKIICNL 

       490        500        510        520        530        540 
PEQAKIRYAS TLVLGRYTEW TAKHPELLEV QLQYIFNGFQ LHEGSSDMQS IITASSHALM 

       550        560        570        580        590        600 
FFCSDCSKLL VGYIDQLINF FLNVQSSIDI ESQFELCQGL SAVINNQPEA KVSVIFQKLV 

       610        620        630        640        650        660 
DDNLRQIEAL IPQWKANPTL LAPQIADKID LLYALFEELK PRYNYPQQGS EPLLPRIEFI 

       670        680        690        700        710        720 
WKALRTLLVD AGAMTDSIIV ERVAKLLRRI FERFHVFCEP ILPSVAEFLI QGYLTTGFGS 

       730        740        750        760        770        780 
YLWCSGSLIV IFGDDESFPI SPSLKDAVWK FALSQCETFI LNFNKFDKLQ LNDYHEAIID 

       790        800        810        820        830        840 
FFSLISDLIM FYPGAFLNST ELLGPVLNVA LECVNKLDNY DAYICILRCL DDIISWGFKT 

       850        860        870        880        890        900 
PPISTVSIEI VPDEWRKQVI NEVVIAHGNQ LILVLFIGLV TTFENTAHSD AISCIVKCLR 

       910        920        930        940        950        960 
ILTEANNNDA TICIDWIYKV VEQLGQVTLN ERDNLAKAVV EGLNSKDYRK VREGIRAFVG 

       970 
WYSRKNINSR FE 

References and documentation are available.

Number of amino acids: 972

Molecular weight: 110745.38

Theoretical pI: 4.68

Amino acid composition: 
Ala (A)  54	  5.6%
Arg (R)  33	  3.4%
Asn (N)  57	  5.9%
Asp (D)  56	  5.8%
Cys (C)  21	  2.2%
Gln (Q)  49	  5.0%
Glu (E)  70	  7.2%
Gly (G)  29	  3.0%
His (H)  13	  1.3%
Ile (I)  88	  9.1%
Leu (L) 132	 13.6%
Lys (K)  44	  4.5%
Met (M)  13	  1.3%
Phe (F)  56	  5.8%
Pro (P)  37	  3.8%
Ser (S)  79	  8.1%
Thr (T)  46	  4.7%
Trp (W)  15	  1.5%
Tyr (Y)  24	  2.5%
Val (V)  56	  5.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 126
Total number of positively charged residues (Arg + Lys): 77

Atomic composition:

Carbon      C	      5026
Hydrogen    H	      7870
Nitrogen    N	      1262
Oxygen      O	      1480
Sulfur      S	        34

Formula: C5026H7870N1262O1480S34
Total number of atoms: 15672

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   119510
Abs 0.1% (=1 g/l)   1.079, assuming all pairs of Cys residues form cystines


Ext. coefficient   118260
Abs 0.1% (=1 g/l)   1.068, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 38.69
This classifies the protein as stable.



Aliphatic index: 110.53

Grand average of hydropathicity (GRAVY): 0.082