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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDNVVDPWYI NPSGFAKDTQ DEEYVQHHDN VNPTIPPPDN YILNNENDDG LDNLLGMDYY

70 80 90 100 110 120
NIDDLLTQEL RDLDIPLVPS PKTGDGSSDK KNIDRTWNLG DENNKVSHYS KKSMSSHKRG

130 140 150 160 170 180
LSGTAIFGFL GHNKTLSISS LQQSILNMSK DPQPMELINE LGNHNTVKNN NDDFDHIREN

190 200 210 220 230 240
DGENSYLSQV LLKQQEELRI ALEKQKEVNE KLEKQLRDNQ IQQEKLRKVL EEQEEVAQKL

250 260 270 280 290 300
VSGATNSNSK PGSPVILKTP AMQNGRMKDN AIIVTTNSAN GGYQFPPPTL ISPRMSNTSI

310 320 330 340 350 360
NGSPSRKYHR QRYPNKSPES NGLNLFSSNS GYLRDSELLS FSPQNYNLNL DGLTYNDHNN

370 380 390 400 410 420
TSDKNNNDKK NSTGDNIFRL FEKTSPGGLS ISPRINGNSL RSPFLVGTDK SRDDRYAAGT

430 440 450 460 470 480
FTPRTQLSPI HKKRESVVST VSTISQLQDD TEPIHMRNTQ NPTLRNANAL ASSSVLPPIP

490 500 510 520 530 540
GSSNNTPIKN SLPQKHVFQH TPVKAPPKNG SNLAPLLNAP DLTDHQLEIK TPIRNNSHCE

550 560 570 580 590 600
VESYPQVPPV THDIHKSPTL HSTSPLPDEI IPRTTPMKIT KKPTTLPPGT IDQYVKELPD

610 620 630 640 650 660
KLFECLYPNC NKVFKRRYNI RSHIQTHLQD RPYSCDFPGC TKAFVRNHDL IRHKISHNAK

670 680 690 700 710 720
KYICPCGKRF NREDALMVHR SRMICTGGKK LEHSINKKLT SPKKSLLDSP HDTSPVKETI

730 740 750 760 770
ARDKDGSVLM KMEEQLRDDM RKHGLLDPPP STAAHEQNSN RTLSNETDAL


References and documentation are available.

Number of amino acids: 770 Molecular weight: 86633.98 Theoretical pI: 8.47
Amino acid composition: 
Ala (A) 23 3.0% Arg (R) 38 4.9% Asn (N) 73 9.5% Asp (D) 54 7.0% Cys (C) 8 1.0% Gln (Q) 33 4.3% Glu (E) 38 4.9% Gly (G) 36 4.7% His (H) 28 3.6% Ile (I) 41 5.3% Leu (L) 71 9.2% Lys (K) 59 7.7% Met (M) 15 1.9% Phe (F) 17 2.2% Pro (P) 62 8.1% Ser (S) 73 9.5% Thr (T) 49 6.4% Trp (W) 2 0.3% Tyr (Y) 20 2.6% Val (V) 30 3.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 92 Total number of positively charged residues (Arg + Lys): 97 Atomic composition: Carbon C 3755 Hydrogen H 5995 Nitrogen N 1107 Oxygen O 1203 Sulfur S 23 Formula: C3755H5995N1107O1203S23 Total number of atoms: 12083 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41300 Abs 0.1% (=1 g/l) 0.477, assuming all pairs of Cys residues form cystines Ext. coefficient 40800 Abs 0.1% (=1 g/l) 0.471, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 53.52 This classifies the protein as unstable. Aliphatic index: 71.01 Grand average of hydropathicity (GRAVY): -0.909