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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDPEQEISNE TLETILVSST KGSNNNNKKM EEEMKKKVSR GELGGEAQNC PRCESPNTKF

70 80 90 100 110 120
CYYNNYSLSQ PRYFCKSCRR YWTKGGTLRN VPVGGGCRRN KRSSSSAFSK NNNNKSINFH

130 140 150 160 170 180
TDPLQNPLIT GMPPSSFGYD HSIDLNLAFA TLQKHHLSSQ ATTPSFGFGG DLSIYGNSTN

190 200 210 220 230 240
DVGIFGGQNG TYNNSLCYGF MSGNGNNNQN EIKMASTLGM SLEGNERKQE NVNNNNNNSE

250 260 270 280
NPSKVFWGFP WQMTGDSAGV VPEIDPGRES WNGMVSSWNN GLLNTPLV


References and documentation are available.

Number of amino acids: 288 Molecular weight: 31782.02 Theoretical pI: 8.11
Amino acid composition: 
Ala (A) 7 2.4% Arg (R) 11 3.8% Asn (N) 41 14.2% Asp (D) 8 2.8% Cys (C) 7 2.4% Gln (Q) 10 3.5% Glu (E) 17 5.9% Gly (G) 30 10.4% His (H) 4 1.4% Ile (I) 9 3.1% Leu (L) 18 6.2% Lys (K) 16 5.6% Met (M) 9 3.1% Phe (F) 12 4.2% Pro (P) 15 5.2% Ser (S) 33 11.5% Thr (T) 16 5.6% Trp (W) 5 1.7% Tyr (Y) 9 3.1% Val (V) 11 3.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 25 Total number of positively charged residues (Arg + Lys): 27 Atomic composition: Carbon C 1363 Hydrogen H 2097 Nitrogen N 401 Oxygen O 448 Sulfur S 16 Formula: C1363H2097N401O448S16 Total number of atoms: 4325 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41285 Abs 0.1% (=1 g/l) 1.299, assuming all pairs of Cys residues form cystines Ext. coefficient 40910 Abs 0.1% (=1 g/l) 1.287, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 49.03 This classifies the protein as unstable. Aliphatic index: 50.07 Grand average of hydropathicity (GRAVY): -0.849