ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDPHNPIVLD QGTGFVKIGR AGENFPDYTF PSIVGRPILR AEERASVATP LKDIMIGDEA 

        70         80         90        100        110        120 
SEVRSYLQIS YPMENGIIKN WTDMELLWDY AFFEQMKLPS TSNGKILLTE PPMNPLKNRE 

       130        140        150        160        170        180 
KMCEVMFEKY DFGGVYVAIQ AVLALYAQGL SSGVVVDSGD GVTHIVPVYE SVVLSHLTRR 

       190        200        210        220        230        240 
LDVAGRDVTR HLIDLLSRRG YAFNRTADFE TVRQIKEKLC YVSYDLDLDT KLARETTALV 

       250        260        270        280        290        300 
ESYELPDGRT IKVGQERFEA PECLFQPGLV DVEQPGVGEL LFNTVQSADV DIRSSLYKAI 

       310        320        330        340        350        360 
VLSGGSSMYP GLPSRLEKEL KQLWFSRVLH NDPSRLDKFK VRIEDPPRRK HMVFIGGAVL 

       370        380        390 
ASIMADKDHM WLSKQEWQES GPSAMTKFGP R 

References and documentation are available.

Number of amino acids: 391

Molecular weight: 44073.52

Theoretical pI: 5.54

Amino acid composition: 
Ala (A)  22	  5.6%
Arg (R)  25	  6.4%
Asn (N)  10	  2.6%
Asp (D)  26	  6.6%
Cys (C)   3	  0.8%
Gln (Q)  13	  3.3%
Glu (E)  28	  7.2%
Gly (G)  28	  7.2%
His (H)   7	  1.8%
Ile (I)  20	  5.1%
Leu (L)  39	 10.0%
Lys (K)  21	  5.4%
Met (M)  13	  3.3%
Phe (F)  16	  4.1%
Pro (P)  23	  5.9%
Ser (S)  28	  7.2%
Thr (T)  17	  4.3%
Trp (W)   5	  1.3%
Tyr (Y)  14	  3.6%
Val (V)  33	  8.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 54
Total number of positively charged residues (Arg + Lys): 46

Atomic composition:

Carbon      C	      1974
Hydrogen    H	      3105
Nitrogen    N	       529
Oxygen      O	       582
Sulfur      S	        16

Formula: C1974H3105N529O582S16
Total number of atoms: 6206

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    48485
Abs 0.1% (=1 g/l)   1.100, assuming all pairs of Cys residues form cystines


Ext. coefficient    48360
Abs 0.1% (=1 g/l)   1.097, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.60
This classifies the protein as unstable.



Aliphatic index: 88.95

Grand average of hydropathicity (GRAVY): -0.250