ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDPIREGEVA HEGDSVYTLN DFTKLEKIGE GTYGVVYKGK NRRTNAMVAM KKIRLESEDE 

        70         80         90        100        110        120 
GVPSTAVREI SLLKELQHPN VVGLEAVIMQ ENRLFLIFEF LSFDLKRYMD QLGKDEYLPL 

       130        140        150        160        170        180 
ETLKSYTFQI LQAMCFCHQR RVIHRDLKPQ NLLVDNNGAI KLADFGLARA IGIPIRVYTH 

       190        200        210        220        230        240 
EVVTLWYRAP EILMGAQRYS MGVDMWSIGC IFAEMATKKP LFQGDSEIDE LFRIFRVLGT 

       250        260        270        280        290        300 
PTELEWNGVE SLPDYKATFP KWRENFLRDK FYDKKTGKHL LDDTAFSLLE GLLIYDPSLR 

       310        320        330 
LNAKKALVHP YFDNMDTSKL PAGNYRGELE LF 

References and documentation are available.

Number of amino acids: 332

Molecular weight: 38295.19

Theoretical pI: 5.89

Amino acid composition: 
Ala (A)  19	  5.7%
Arg (R)  20	  6.0%
Asn (N)  13	  3.9%
Asp (D)  21	  6.3%
Cys (C)   3	  0.9%
Gln (Q)   9	  2.7%
Glu (E)  27	  8.1%
Gly (G)  22	  6.6%
His (H)   7	  2.1%
Ile (I)  18	  5.4%
Leu (L)  41	 12.3%
Lys (K)  23	  6.9%
Met (M)  11	  3.3%
Phe (F)  18	  5.4%
Pro (P)  14	  4.2%
Ser (S)  13	  3.9%
Thr (T)  16	  4.8%
Trp (W)   4	  1.2%
Tyr (Y)  14	  4.2%
Val (V)  19	  5.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 48
Total number of positively charged residues (Arg + Lys): 43

Atomic composition:

Carbon      C	      1735
Hydrogen    H	      2709
Nitrogen    N	       455
Oxygen      O	       494
Sulfur      S	        14

Formula: C1735H2709N455O494S14
Total number of atoms: 5407

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    42985
Abs 0.1% (=1 g/l)   1.122, assuming all pairs of Cys residues form cystines


Ext. coefficient    42860
Abs 0.1% (=1 g/l)   1.119, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 23.29
This classifies the protein as stable.



Aliphatic index: 91.63

Grand average of hydropathicity (GRAVY): -0.277