ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDPQTLITKA NKVSYYGNPT SKESWRYDWY QPSKVSSNVQ QPQQQLGDME NNLEKYPFRY 

        70         80         90        100        110        120 
KTWLRNQEDE KNLQRESCED ILDLKEFDRR ILKKSLMTSH TKGDTSKATG APSANQGDEA 

       130        140        150 
LSVDDIRGAV GNSEAIPGLS AGVNNDNTKE SKDVKMN 

References and documentation are available.

Number of amino acids: 157

Molecular weight: 17794.63

Theoretical pI: 5.52

Amino acid composition: 
Ala (A)   8	  5.1%
Arg (R)   7	  4.5%
Asn (N)  13	  8.3%
Asp (D)  13	  8.3%
Cys (C)   1	  0.6%
Gln (Q)  10	  6.4%
Glu (E)  11	  7.0%
Gly (G)   9	  5.7%
His (H)   1	  0.6%
Ile (I)   5	  3.2%
Leu (L)  11	  7.0%
Lys (K)  15	  9.6%
Met (M)   4	  2.5%
Phe (F)   2	  1.3%
Pro (P)   7	  4.5%
Ser (S)  15	  9.6%
Thr (T)   9	  5.7%
Trp (W)   3	  1.9%
Tyr (Y)   6	  3.8%
Val (V)   7	  4.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 24
Total number of positively charged residues (Arg + Lys): 22

Atomic composition:

Carbon      C	       764
Hydrogen    H	      1209
Nitrogen    N	       221
Oxygen      O	       259
Sulfur      S	         5

Formula: C764H1209N221O259S5
Total number of atoms: 2458

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    25440
Abs 0.1% (=1 g/l)   1.430, assuming all pairs of Cys residues form cystines


Ext. coefficient    25440
Abs 0.1% (=1 g/l)   1.430, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.69
This classifies the protein as stable.



Aliphatic index: 57.77

Grand average of hydropathicity (GRAVY): -1.131