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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDPTSRPAIV IDNGTGYTKM GFAGNVEPCF ILPTVVAVNE SFLNQSKSSS KATWQTQHNA

70 80 90 100 110 120
GVAADLDFYI GDEALAKSRS SSTHNLHYPI EHGQVEDWDA MERYWQQCIF NYLRCDPEDH

130 140 150 160 170 180
YFLLTESPLT PPESREYTGE ILFETFNVPG LYIAVNSVLA LAAGYTTSKC EMTGVVVDVG

190 200 210 220 230 240
DGATHVVPVA EGYVIGSCIK SIPIAGKDVT LFIQQLMRER GENIPPEDSF DVARKVKEMY

250 260 270 280 290 300
CYTCSDIVKE FNKHDKEPAK YIKQWKGVKP KTGAPYTCDV GYERFLGPEV FFNPEIYSND

310 320 330 340 350 360
FTTTLPAVID KCIQSAPIDT RRALYKNIVL SGGSTMFKDF GRRLQRDLKK IVDARVLANN

370 380 390 400 410 420
ARTGGEITSQ PVEVNVVSHP VQRFAVWFGG SVLSSTPEFF ASCRTKEEYE EYGASICRTN


PVFKGMY


References and documentation are available.

Number of amino acids: 427 Molecular weight: 47659.97 Theoretical pI: 5.43
Amino acid composition: 
Ala (A) 29 6.8% Arg (R) 19 4.4% Asn (N) 18 4.2% Asp (D) 23 5.4% Cys (C) 11 2.6% Gln (Q) 13 3.0% Glu (E) 30 7.0% Gly (G) 30 7.0% His (H) 8 1.9% Ile (I) 24 5.6% Leu (L) 23 5.4% Lys (K) 24 5.6% Met (M) 8 1.9% Phe (F) 22 5.2% Pro (P) 25 5.9% Ser (S) 29 6.8% Thr (T) 29 6.8% Trp (W) 5 1.2% Tyr (Y) 20 4.7% Val (V) 37 8.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 53 Total number of positively charged residues (Arg + Lys): 43 Atomic composition: Carbon C 2133 Hydrogen H 3274 Nitrogen N 560 Oxygen O 643 Sulfur S 19 Formula: C2133H3274N560O643S19 Total number of atoms: 6629 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 57925 Abs 0.1% (=1 g/l) 1.215, assuming all pairs of Cys residues form cystines Ext. coefficient 57300 Abs 0.1% (=1 g/l) 1.202, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.85 This classifies the protein as unstable. Aliphatic index: 74.85 Grand average of hydropathicity (GRAVY): -0.275