ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDQALYSLET RFEQFQRYEQ IFGFLFDLKK LQSASDDSLM ASCTNLKDAL THGTHSDILA 

        70         80         90        100        110        120 
SDLFYELKIL REALPKEVRR PIEVLDFLQK VEGCYPNSWI AYQVLLTIPV SVASAERSFS 

       130        140        150        160        170 
KLKLIKSYLR SSMSQERLSD LAILSIERAL VREVDFERLA NDFVGKKGRR ITL 

References and documentation are available.

Number of amino acids: 173

Molecular weight: 19948.02

Theoretical pI: 6.75

Amino acid composition: 
Ala (A)  12	  6.9%
Arg (R)  13	  7.5%
Asn (N)   3	  1.7%
Asp (D)  11	  6.4%
Cys (C)   2	  1.2%
Gln (Q)   8	  4.6%
Glu (E)  13	  7.5%
Gly (G)   5	  2.9%
His (H)   2	  1.2%
Ile (I)  10	  5.8%
Leu (L)  26	 15.0%
Lys (K)  11	  6.4%
Met (M)   3	  1.7%
Phe (F)  10	  5.8%
Pro (P)   4	  2.3%
Ser (S)  18	 10.4%
Thr (T)   6	  3.5%
Trp (W)   1	  0.6%
Tyr (Y)   6	  3.5%
Val (V)   9	  5.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 24
Total number of positively charged residues (Arg + Lys): 24

Atomic composition:

Carbon      C	       898
Hydrogen    H	      1435
Nitrogen    N	       239
Oxygen      O	       263
Sulfur      S	         5

Formula: C898H1435N239O263S5
Total number of atoms: 2840

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    14565
Abs 0.1% (=1 g/l)   0.730, assuming all pairs of Cys residues form cystines


Ext. coefficient    14440
Abs 0.1% (=1 g/l)   0.724, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 46.09
This classifies the protein as unstable.



Aliphatic index: 103.18

Grand average of hydropathicity (GRAVY): -0.139