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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDQEIEIPSF FLCPISLDIM KDPVIVSTGI TYDRESIEKW LFSGKKNSCP VTKQVITETD

70 80 90 100 110 120
LTPNHTLRRL IQSWCTLNAS YGIERIPTPK PPICKSEIEK LIKESSSSHL NQVKCLKRLR

130 140 150 160 170 180
QIVSENTTNK RCLEAAEVPE FLANIVSNSV DTYNSPSSSL SSSNLNDMCQ SNMLENRFDS

190 200 210 220 230 240
SRSLMDEALS VLYHLDTSET ALKSLLNNKK GTNLVKTLTK IMQRGIYESR AYAALLLKKL

250 260 270 280 290 300
LEVADPMQII LLERELFGEV IQILHDQISH KATRSAMQIL VITCPWGRNR HKAVEGGTIS

310 320 330 340 350 360
MIIELLMDDT FSSERRNSEM AMVVLDMLCQ CAEGRAEFLN HGAAIAVVSK KILRVSQITS

370 380 390 400 410 420
ERAVRVLLSV GRFCATPSLL QEMLQLGVVA KLCLVLQVSC GNKTKEKAKE LLKLHARVWR

430
ESPCVPRNLY DSYPA


References and documentation are available.

Number of amino acids: 435 Molecular weight: 48876.87 Theoretical pI: 8.56
Amino acid composition: 
Ala (A) 25 5.7% Arg (R) 25 5.7% Asn (N) 21 4.8% Asp (D) 16 3.7% Cys (C) 14 3.2% Gln (Q) 16 3.7% Glu (E) 32 7.4% Gly (G) 14 3.2% His (H) 8 1.8% Ile (I) 31 7.1% Leu (L) 54 12.4% Lys (K) 29 6.7% Met (M) 14 3.2% Phe (F) 9 2.1% Pro (P) 17 3.9% Ser (S) 45 10.3% Thr (T) 24 5.5% Trp (W) 4 0.9% Tyr (Y) 8 1.8% Val (V) 29 6.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 48 Total number of positively charged residues (Arg + Lys): 54 Atomic composition: Carbon C 2143 Hydrogen H 3528 Nitrogen N 596 Oxygen O 646 Sulfur S 28 Formula: C2143H3528N596O646S28 Total number of atoms: 6941 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 34795 Abs 0.1% (=1 g/l) 0.712, assuming all pairs of Cys residues form cystines Ext. coefficient 33920 Abs 0.1% (=1 g/l) 0.694, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 50.74 This classifies the protein as unstable. Aliphatic index: 101.29 Grand average of hydropathicity (GRAVY): -0.115