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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDQLSDSYAL YNQPVVIDNG SGIIKAGFSG EERPKALEYC LVGNTKYDKV MLEGLQGDTF

70 80 90 100 110 120
IGNNAQKLRG LLKLRYPIKH GVVEDWDSME LIWSYVLNEV LQLQNIGEHP LLITEAPMNP

130 140 150 160 170 180
LKNREQMAQV LFETFDVSAL YVSNPAVLSL YASGRTTGCV VDCGEGYCST VPIYDGFALP

190 200 210 220 230 240
ASMMRMDIGG ADITEQLQFQ LRKSAGVSLF SSSEREIVRT MKEKVCYLAK NIKKEEEKYL

250 260 270 280 290 300
QGTQDLISTF KLPDGRCIEV GNDRYRAPEI LFSPQIIGLG YDGLSDMCMQ SIWKVDLDLR

310 320 330 340 350 360
KPLLSSIILS GGTTTLKGFG DRMLWDLEAL TKGTSKIKII APSERKYTTW IGGSILTGLS

370 380
TFQRLWTKKS DWLEDSTRVY SNLM


References and documentation are available.

Number of amino acids: 384 Molecular weight: 42995.50 Theoretical pI: 5.40
Amino acid composition: 
Ala (A) 17 4.4% Arg (R) 17 4.4% Asn (N) 13 3.4% Asp (D) 23 6.0% Cys (C) 7 1.8% Gln (Q) 16 4.2% Glu (E) 24 6.2% Gly (G) 33 8.6% His (H) 2 0.5% Ile (I) 26 6.8% Leu (L) 46 12.0% Lys (K) 25 6.5% Met (M) 13 3.4% Phe (F) 11 2.9% Pro (P) 14 3.6% Ser (S) 31 8.1% Thr (T) 22 5.7% Trp (W) 7 1.8% Tyr (Y) 16 4.2% Val (V) 21 5.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 47 Total number of positively charged residues (Arg + Lys): 42 Atomic composition: Carbon C 1919 Hydrogen H 3046 Nitrogen N 500 Oxygen O 577 Sulfur S 20 Formula: C1919H3046N500O577S20 Total number of atoms: 6062 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 62715 Abs 0.1% (=1 g/l) 1.459, assuming all pairs of Cys residues form cystines Ext. coefficient 62340 Abs 0.1% (=1 g/l) 1.450, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 35.04 This classifies the protein as stable. Aliphatic index: 93.41 Grand average of hydropathicity (GRAVY): -0.171