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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDRDTKLAFR LRGSHSRRTD DIDDDVIVFK TPNAVYREEN SPIQSPVQPI LSSPKLANSF

70 80 90 100 110 120
EFPITTNNVN AQDRHEHGYQ PLDAEDYPMI DSENKSLISE SPQNVRNDED LTTRYNFDDI

130 140 150 160 170 180
PIRQLSSSIT SVTTIDVLSS LFINLFENDL IPQALKDFNK SDDDQFRKLL YKLDLRLFQT

190 200 210 220 230 240
ISDQMTRDLK DILDINVSNN ELCYQLKQVL ARKEDLNQQI ISVRNEIQEL KAGKDWHDLQ

250 260 270 280 290 300
NEQAKLNDKV KLNKRLNDLT STLLGKYEGD RKIMSQDSED DSIRDDSNIL DIAHFVDLMD

310 320
PYNGLLKKIN KINENLSNEL QPSL


References and documentation are available.

Number of amino acids: 324 Molecular weight: 37461.81 Theoretical pI: 4.73
Amino acid composition: 
Ala (A) 10 3.1% Arg (R) 18 5.6% Asn (N) 28 8.6% Asp (D) 40 12.3% Cys (C) 1 0.3% Gln (Q) 19 5.9% Glu (E) 18 5.6% Gly (G) 6 1.9% His (H) 5 1.5% Ile (I) 25 7.7% Leu (L) 39 12.0% Lys (K) 22 6.8% Met (M) 5 1.5% Phe (F) 11 3.4% Pro (P) 13 4.0% Ser (S) 28 8.6% Thr (T) 14 4.3% Trp (W) 1 0.3% Tyr (Y) 8 2.5% Val (V) 13 4.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 58 Total number of positively charged residues (Arg + Lys): 40 Atomic composition: Carbon C 1633 Hydrogen H 2612 Nitrogen N 458 Oxygen O 538 Sulfur S 6 Formula: C1633H2612N458O538S6 Total number of atoms: 5247 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 17420 Abs 0.1% (=1 g/l) 0.465, assuming all pairs of Cys residues form cystines Ext. coefficient 17420 Abs 0.1% (=1 g/l) 0.465, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 41.23 This classifies the protein as unstable. Aliphatic index: 91.76 Grand average of hydropathicity (GRAVY): -0.744