Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDRESALRLE TPRRELISRA RSFSLATSKN RCKKMDNEKA LRFELECRRT GKCREIVADV

70 80 90 100 110 120
QHSRMPRHME QEACSLAAKS IMTYHLEHDI ARHLKMAFDR EYGPDWHCIC GKHFGSFVTF

130 140 150 160 170 180
EPDSFIYFRI GTIAFMLFKT SLQRLPIMEK HLENVKLTPT TILGRSRLMT PKSEDDEEST


SASDVS


References and documentation are available.

Number of amino acids: 186 Molecular weight: 21646.89 Theoretical pI: 8.76
Amino acid composition: 
Ala (A) 12 6.5% Arg (R) 19 10.2% Asn (N) 3 1.6% Asp (D) 10 5.4% Cys (C) 6 3.2% Gln (Q) 3 1.6% Glu (E) 17 9.1% Gly (G) 6 3.2% His (H) 8 4.3% Ile (I) 10 5.4% Leu (L) 16 8.6% Lys (K) 12 6.5% Met (M) 9 4.8% Phe (F) 10 5.4% Pro (P) 7 3.8% Ser (S) 17 9.1% Thr (T) 12 6.5% Trp (W) 1 0.5% Tyr (Y) 3 1.6% Val (V) 5 2.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 27 Total number of positively charged residues (Arg + Lys): 31 Atomic composition: Carbon C 940 Hydrogen H 1506 Nitrogen N 278 Oxygen O 279 Sulfur S 15 Formula: C940H1506N278O279S15 Total number of atoms: 3018 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 10345 Abs 0.1% (=1 g/l) 0.478, assuming all pairs of Cys residues form cystines Ext. coefficient 9970 Abs 0.1% (=1 g/l) 0.461, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 48.26 This classifies the protein as unstable. Aliphatic index: 68.76 Grand average of hydropathicity (GRAVY): -0.566