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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDRSLGWQGN SVPEDRTEAG IKRFLEDTTD DGELSKFVKD FSGNASCHPP EAKTWASRPQ

70 80 90 100 110 120
VPEPRPQAPD LYDDDLEFRP PSRPQSSDNQ QYFCAPAPLS PSARPRSPWG KLDPYDSSED

130 140 150 160 170 180
DKEYVGFATL PNQVHRKSVK KGFDFTLMVA GESGLGKSTL VNSLFLTDLY RDRKLLGAEE

190 200 210 220 230 240
RIMQTVEITK HAVDIEEKGV RLRLTIVDTP GFGDAVNNTE CWKPVAEYID QQFEQYFRDE

250 260 270 280 290 300
SGLNRKNIQD NRVHCCLYFI SPFGHGLRPL DVEFMKALHQ RVNIVPILAK ADTLTPPEVD

310 320 330 340 350 360
HKKRKIREEI EHFGIKIYQF PDCDSDEDED FKLQDQALKE SIPFAVIGSN TVVEARGRRV

370 380 390 400 410 420
RGRLYPWGIV EVENPGHCDF VKLRTMLVRT HMQDLKDVTR ETHYENYRAQ CIQSMTRLVV

430 440 450 460 470
KERNRNKLTR ESGTDFPIPA VPPGTDPETE KLIREKDEEL RRMQEMLHKI QKQMKENY


References and documentation are available.

Number of amino acids: 478 Molecular weight: 55098.16 Theoretical pI: 5.77
Amino acid composition: 
Ala (A) 22 4.6% Arg (R) 38 7.9% Asn (N) 17 3.6% Asp (D) 39 8.2% Cys (C) 8 1.7% Gln (Q) 22 4.6% Glu (E) 41 8.6% Gly (G) 26 5.4% His (H) 12 2.5% Ile (I) 21 4.4% Leu (L) 36 7.5% Lys (K) 32 6.7% Met (M) 10 2.1% Phe (F) 21 4.4% Pro (P) 34 7.1% Ser (S) 25 5.2% Thr (T) 25 5.2% Trp (W) 5 1.0% Tyr (Y) 13 2.7% Val (V) 31 6.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 80 Total number of positively charged residues (Arg + Lys): 70 Atomic composition: Carbon C 2426 Hydrogen H 3804 Nitrogen N 692 Oxygen O 741 Sulfur S 18 Formula: C2426H3804N692O741S18 Total number of atoms: 7681 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 47370 Abs 0.1% (=1 g/l) 0.860, assuming all pairs of Cys residues form cystines Ext. coefficient 46870 Abs 0.1% (=1 g/l) 0.851, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 48.00 This classifies the protein as unstable. Aliphatic index: 69.92 Grand average of hydropathicity (GRAVY): -0.786