ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDSHSSHLNA ANRSRSSQTP SPSHSASASV TSSLHKRKLA ATTAANAAAS EDHAPPSSSF 

        70         80         90        100        110        120 
PPSSFSADTR DGALTSNDEL ESISARGADT DSDPDESEDI VVDDDEDEFA PEQDQDSSIR 

       130        140        150        160        170        180 
TFTAARLDSS SGVNGSSRNT KLKTESSTVK LESSDGGKDG GSSVVGTGVS GTVGGSSISG 

       190        200        210        220        230        240 
LVPKDESVKV LAENFQTSGA YIAREEALKR EEQAGRLKFV CYSNDSIDEH MMCLIGLKNI 

       250        260        270        280        290        300 
FARQLPNMPK EYIVRLLMDR KHKSVMVLRG NLVVGGITYR PYHSQKFGEI AFCAITADEQ 

       310        320        330        340        350        360 
VKGYGTRLMN HLKQHARDVD GLTHFLTYAD NNAVGYFVKQ GFTKEIYLEK DVWHGFIKDY 

       370        380        390        400        410        420 
DGGLLMECKI DPKLPYTDLS SMIRQQRKAI DERIRELSNC QNVYPKIEFL KNEAGIPRKI 

       430        440        450        460        470        480 
IKVEEIRGLR EAGWTPDQWG HTRFKLFNGS ADMVTNQKQL NALMRALLKT MQDHADAWPF 

       490        500        510        520        530        540 
KEPVDSRDVP DYYDIIKDPI DLKVIAKRVE SEQYYVTLDM FVADARRMFN NCRTYNSPDT 

       550        560 
IYYKCATRLE THFHSKVQAG LQSGAKSQ 

References and documentation are available.

Number of amino acids: 568

Molecular weight: 63123.60

Theoretical pI: 6.01

Amino acid composition: 
Ala (A)  45	  7.9%
Arg (R)  33	  5.8%
Asn (N)  23	  4.0%
Asp (D)  46	  8.1%
Cys (C)   7	  1.2%
Gln (Q)  21	  3.7%
Glu (E)  34	  6.0%
Gly (G)  36	  6.3%
His (H)  16	  2.8%
Ile (I)  28	  4.9%
Leu (L)  40	  7.0%
Lys (K)  38	  6.7%
Met (M)  14	  2.5%
Phe (F)  20	  3.5%
Pro (P)  22	  3.9%
Ser (S)  58	 10.2%
Thr (T)  31	  5.5%
Trp (W)   4	  0.7%
Tyr (Y)  19	  3.3%
Val (V)  33	  5.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 80
Total number of positively charged residues (Arg + Lys): 71

Atomic composition:

Carbon      C	      2747
Hydrogen    H	      4331
Nitrogen    N	       785
Oxygen      O	       881
Sulfur      S	        21

Formula: C2747H4331N785O881S21
Total number of atoms: 8765

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    50685
Abs 0.1% (=1 g/l)   0.803, assuming all pairs of Cys residues form cystines


Ext. coefficient    50310
Abs 0.1% (=1 g/l)   0.797, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 37.64
This classifies the protein as stable.



Aliphatic index: 71.46

Grand average of hydropathicity (GRAVY): -0.581