ProtParam
User-provided sequence:
10 20 30 40 50 60
MDSIDEQIAI KRKELQSLQK ITSLTDGLKI QLTELNEQIK EMGMNADSVA QLMNNWDSII
70 80 90 100 110 120
NNISQASLGL LQYAEGDYEI GPWKDSKKKE SEQSNETGLE AQENDKNDED NDEDEDLVPL
130
PETMVRIRVD GNE
References and
documentation are available.
Number of amino acids: 133
Molecular weight: 15071.56
Theoretical pI: 4.13
Total number of negatively charged residues (Asp + Glu): 31
Total number of positively charged residues (Arg + Lys): 13
Atomic composition:
Carbon C 639
Hydrogen H 1033
Nitrogen N 175
Oxygen O 234
Sulfur S 5
Formula: C
639H
1033N
175O
234S
5
Total number of atoms: 2086
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 13980
Abs 0.1% (=1 g/l) 0.928
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 49.79
This classifies the protein as unstable.
Aliphatic index: 83.61
Grand average of hydropathicity (GRAVY): -0.917