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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MDSLSKKIQN LGIHDIRNAA RFAQNVIVQY EPYQIDIRRA TNTDAWGPTP KHLAKVLRNR

70 80 90 100 110 120
YQVPLYLMTE YTLKRLVDHI ATRPKNLYEK ARKDYVNYGS EWRVVLKCLV VIEFLLLNVD

130 140 150 160 170 180
TGDELNQIRS CLLTHKHILT REIAQFKVKF SNDGKMEIHE RGIRKKGELI LQYLEDSQFL

190 200 210 220 230 240
KKERAKNKKN ALKIRQQGES SIYNANQIST SASYDNIDDD EFDADADGFD SEMDANNVTN

250 260 270 280 290 300
FNVPVETEAN SNTRRRSHME EQRRQRREIL REQIKNKEQQ RKRKQQQDSI PDLIDLDDST

310 320 330 340 350 360
STTNNITIDN GNNDNKNNNI NSNSDDDDDE FGDFQSETSP DTTAPKTSNS KIDDLLDWDG

370 380 390 400 410
PKSDTDTTAA AQTSLPFAEK KQQKARPQAT KDKSKGNDAF SDLFSYSKSL V


References and documentation are available.

Number of amino acids: 411 Molecular weight: 47321.46 Theoretical pI: 6.07
Amino acid composition: 
Ala (A) 25 6.1% Arg (R) 27 6.6% Asn (N) 35 8.5% Asp (D) 42 10.2% Cys (C) 2 0.5% Gln (Q) 25 6.1% Glu (E) 25 6.1% Gly (G) 13 3.2% His (H) 7 1.7% Ile (I) 26 6.3% Leu (L) 31 7.5% Lys (K) 36 8.8% Met (M) 5 1.2% Phe (F) 13 3.2% Pro (P) 12 2.9% Ser (S) 30 7.3% Thr (T) 26 6.3% Trp (W) 3 0.7% Tyr (Y) 12 2.9% Val (V) 16 3.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 67 Total number of positively charged residues (Arg + Lys): 63 Atomic composition: Carbon C 2044 Hydrogen H 3263 Nitrogen N 605 Oxygen O 674 Sulfur S 7 Formula: C2044H3263N605O674S7 Total number of atoms: 6593 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 34505 Abs 0.1% (=1 g/l) 0.729, assuming all pairs of Cys residues form cystines Ext. coefficient 34380 Abs 0.1% (=1 g/l) 0.727, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.56 This classifies the protein as unstable. Aliphatic index: 71.46 Grand average of hydropathicity (GRAVY): -1.012